ADAMANTANE-1-CARBOXYLIC ACID METHYL ESTER synthesis
- Product Name:ADAMANTANE-1-CARBOXYLIC ACID METHYL ESTER
- CAS Number:711-01-3
- Molecular formula:C12H18O2
- Molecular Weight:194.27
67-56-1
752 suppliers
$7.29/5ml-f
828-51-3
424 suppliers
$10.00/5g
711-01-3
165 suppliers
$40.00/2 g
Yield:711-01-3 100%
Reaction Conditions:
with sulfuric acid at 130; for 0.2 h;Microwave irradiation;
Steps:
Methyl Adamantane-1-carboxylate (8)
b) Microwave Method: A mixture of adamantane-1-carboxylic acid (1 mmol),0.5 ml concentrated sulfuric acid in dry methanol was placedin a closed teflon vessel and irradiated by MW to achieve aconstant temperature of 130 °C for 12 min. Upon completionof the reaction (checked by TLC), the reaction mixture waspoured onto crushed ice to produce a white crystalline solidwhich was filtered, washed with cold water to yield quantitativelymethyl adamantane-1-carboxylate. The product wasidentical with that obtained in method a. Mp 37 °C, literature40°C [25].
References:
Al-Qawasmeh, Raed A.;Salameh, Bader A.;Alrazim, Rami;Aldamen, Murad A.;Voelter, Wolfgang [Letters in Organic Chemistry,2014,vol. 11,# 7,p. 513 - 518]
828-51-3
424 suppliers
$10.00/5g
18107-18-1
209 suppliers
$33.00/5g
711-01-3
165 suppliers
$40.00/2 g
770-71-8
350 suppliers
$12.00/5g
865-33-8
163 suppliers
$12.50/100G
711-01-3
165 suppliers
$40.00/2 g
67-56-1
752 suppliers
$7.29/5ml-f
201230-82-2
1 suppliers
inquiry
768-93-4
73 suppliers
$136.00/5g
711-01-3
165 suppliers
$40.00/2 g