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ChemicalBook CAS DataBase List 5-Bromo-2-fluoro-4-methyl-pyridine
864830-16-0

5-Bromo-2-fluoro-4-methyl-pyridine synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: pyridinium hydrobromide perbromide / tetrahydrofuran / 2.17 h / 20 °C
2.1: nitrosonium tetrafluoroborate / chloroform / 2 h / 0 - 20 °C
2.2: 150 °C

References:

BANYU PHARMACEUTICAL CO., LTD. EP1726590, 2006, A1

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