4-PHENOXYPHENYLMAGNESIUM BROMIDE synthesis
- Product Name:4-PHENOXYPHENYLMAGNESIUM BROMIDE
- CAS Number:21473-02-9
- Molecular formula:C12H9BrMgO
- Molecular Weight:273.41
101-55-3
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21473-02-9
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$228.00/100ml
Yield:-
Reaction Conditions:
with iodine;magnesium in diethyl ether;Inert atmosphere;Reflux;
Steps:
Preparation of arylmagnesium bromides
General procedure: A solution of aryl bromide (0.3 mol) (see Table 1) in diethyl ether (~215 mL) was added to a mixture of Mg turnings (7.29 g, 0.3 mol), diethyl ether (~17 mL), and a catalyst (several iodine crystals) under argon with stirring at such a rate that the ether was boiling, then the mixture was refluxed for 1-1.5 h. Since 1-bromo-2,4-dichlorobenzene (the starting compound for the synthesis of a-hydroxy ester 3e) did not react with magnesium under these conditions, the Grignard reaction for it was carried out in the presence of a large amount of iodine and dibromoethane (4 mL) upon reflux for 2.5 h.
References:
Vasilyeva;Vorobyeva [Russian Chemical Bulletin,2018,vol. 67,# 8,p. 1426 - 1432][Izv. Akad. Nauk, Ser. Khim.,2018,# 8,p. 1426 - 1432,7]
101-55-3
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$8.00/5g
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21473-02-9
43 suppliers
$228.00/100ml