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ChemicalBook CAS DataBase List 4-Iodopyrazole
3469-69-0

4-Iodopyrazole synthesis

4synthesis methods

4-Iodopyrazole is a valuable precursor for the selective construction of highly functionalized organic molecules of synthetic and biological importance. It is synthesised from Pyrazole by substitution reaction,the reantion is with ammonium cerium(IV) nitrate;iodine in acetonitrile.

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Yield:3469-69-0 98%

Reaction Conditions:

with ammonium cerium(IV) nitrate;iodine in acetonitrile at 20; for 3 h;

References:

Rodríguez-Franco, María Isabel;Dorronsoro, Isabel;Hernández-Higueras, Ana I;Antequera, Gema [Tetrahedron Letters,2001,vol. 42,# 5,p. 863 - 865]

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