ChemicalBook CAS DataBase List 1-Benzyl-4-iodo-1H-pyrazole

1-Benzyl-4-iodo-1H-pyrazole synthesis

5synthesis methods

Product Name:1-Benzyl-4-iodo-1H-pyrazole
CAS Number:50877-42-4
Molecular formula:C10H9IN2
Molecular Weight:284.1

3469-69-0 Synthesis

3469-69-0
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$5.00/1g

100-44-7 Synthesis

100-44-7
644 suppliers
$13.50/250G

50877-42-4
135 suppliers
$9.00/100mg

Yield: 79%

Reaction Conditions:

with tetrabutylammomium bromide;potassium hydroxide at 20; for 48 h;

Steps:

5.2 Preparation of 1-benzyl-4-iodopyrazole
0.323 g of benzyl chloride was added dropwise to a solution of 57.0 g of 4-iodopyrazole, 20.0 g of potassium hydroxide and 2.9 g of TBAB in a solution at room temperature, After the dropwise addition, the mixture was stirred at about constant temperature for about 48 hours. The organic layer was washed three times with 40 ° C water and dried over magnesium sulfate to give 66.0 g of a yellow oil product with a GC purity of 97.0% and a yield of 79%.

References:

Dalian AllyChem Co.,Ltd(AllyChem);WANG, XIANXUE;ZHENG, PENG CN103601749, 2016, B Location in patent:Paragraph 0062-0063

3469-69-0 Synthesis

3469-69-0
401 suppliers
$5.00/1g