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ChemicalBook CAS DataBase List 4-Aminophthalhydrazide
3682-14-2

4-Aminophthalhydrazide synthesis

10synthesis methods
-

Yield:3682-14-2 85%

Reaction Conditions:

with 10% Pd/C;hydrogen at 35; under 3040.2 Torr; for 4 h;

Steps:

1.3

Transfer the product B to a 5 L hydrogenation vessel, add 3 g of 10 wt% palladium on carbon palladium, heat to 35 ° C, while the introduction of hydrogen pressure to 4atm, continue to heat constant pressure reaction 4 hours, after the end of the reaction, the hydrogen into nitrogen, Adjust the pH to 3-4 with 35 wt% concentrated hydrochloric acid, continue heating to 100 ° C, stop the introduction of nitrogen, filter hot, and cool the filtrate to HTC, a large number of precipitated precipitation, precipitate out completely after the filter, the filtrate for organic solvent recovery, filter cake with 400ml deionized water washing, drying, to be 214g isluminolide (4-amino phthalide)

References:

CN106810501,2017,A Location in patent:Paragraph 0050

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