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ChemicalBook CAS DataBase List 3-Hydroxytetrahydrofuran
453-20-3

3-Hydroxytetrahydrofuran synthesis

10synthesis methods
-

Yield:453-20-3 96%

Reaction Conditions:

strong acid ion exchange resin (Amberlyst 15, H+ form) in 1,4-dioxane at 100; under 760.051 Torr; for 20 h;Product distribution / selectivity;

Steps:

1

Example 1; Instead of PEG-400 and the para-toluenesulfonic acid catalyst used in ComparativeExample 1, dioxane and a strong acid ion exchange resin (Amberlyst 15, H+ form) containing a sulfonic acid group were used in equal amounts. Then, the reaction was conducted using a batch type reactor under conditions of atmospheric pressure and 1000C for 20 hours. The reaction yield was 96 mol%.

References:

WO2007/81065,2007,A1 Location in patent:Page/Page column 6

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