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ChemicalBook CAS DataBase List 3,4-Dihydro-2H-pyran
110-87-2

3,4-Dihydro-2H-pyran synthesis

14synthesis methods
-

Yield:110-87-2 171 mg (93%)

Reaction Conditions:

in dichloromethane;ethyl acetate;

Steps:

ii.2 ii

Step 2 To a solution of compound 93 (200 mg, 0.55 mmol) in 100 mL of CH2Cl2 was added Grubbs's catalyst (20 mg, 5 mol %) and the mixture was refluxed under argon for 2 hours. The solvent was removed under reduced pressure and the residue was chromatographed (3% EtOAc in hexanes) to provide 171 mg (93%) of dihydropyran 94.

References:

US2004/121947,2004,A1

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