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ChemicalBook CAS DataBase List 2-Ethoxy-4-amino-5-chlorobenzoic acid
108282-38-8

2-Ethoxy-4-amino-5-chlorobenzoic acid synthesis

7synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 5 steps
1: sulfuric acid / 2 h / 20 °C
2: acetic acid / 1 h
3: sodium hydroxide / N,N-dimethyl-formamide
4: N-chloro-succinimide / N,N-dimethyl-formamide
5: sodium hydroxide / ethanol

References:

Deng, Xin;Zhao, Xinxin;Han, Jing;Wang, Jingjie;Huang, Wenlong;Qian, Hai;Ge, Liang [Letters in drug design and discovery,2012,vol. 9,# 5,p. 489 - 493]

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