ChemicalBook CAS DataBase List 2,4-Dimethylphenol

2,4-Dimethylphenol synthesis

11synthesis methods

Product Name:2,4-Dimethylphenol
CAS Number:105-67-9
Molecular formula:C8H10O
Molecular Weight:122.16

synthesis of 2,4-dimethylphenol: 2,4-Dimethylphenol is obtained by sulfonation, salting out, alkali melting and acidification of m-xylene.

55499-44-0 Synthesis

55499-44-0
183 suppliers
$14.00/1g

105-67-9
298 suppliers
$14.00/1g

Yield:105-67-9 99%

Reaction Conditions:

with dihydrogen peroxide in ethanol at 20; for 0.0166667 h;Green chemistry;Solvent;

Steps:

General procedure for the oxidation using H2O2

General procedure: A 25 ml flask was charged with phenylboronic acid (1 mmol). Then 1.6 mL H2O2 and 1 mL EtOH were added under stirring. The reaction was stirred for 1 min, then quenched by water (10 ml). The aqueous layer was extracted with 20 mL ethyl acetate for three times. The combined organic layers were dried over Na2SO4 and concentrated under reduced pressure. The pure product was obtained without flash column chromatography and the purity was determine by TLC.

References:

Dong, Zhenhua;Liu, Mengmeng;Pan, Hongguo [Arkivoc,2021,vol. 2021,# 8]