ChemicalBook CAS DataBase List 2,4-Dimethylbromobenzene

2,4-Dimethylbromobenzene synthesis

8synthesis methods

Product Name:2,4-Dimethylbromobenzene
CAS Number:583-70-0
Molecular formula:C8H9Br
Molecular Weight:185.06

108-38-3
367 suppliers
$10.60/50gm:

583-70-0
238 suppliers
$15.00/5mg

Yield:583-70-0 97%

Reaction Conditions:

with N-Bromosuccinimide in 1,2-dichloro-ethane at 60; for 10 h;Sealed tube;

Steps:

2.6 Typical procedure for the bromination
General procedure: NBS (1.0 mmol) and catalyst 1 (0.1 or 1 mol % Au based on the substrate) were weighted into a 10 mL sealed vessel, and then DCE (2 mL) and the substrate (1.0 mmol) were added. The reaction was stirred at the required temperature for the specified time. After reaction, the catalyst was removed with a magnet, and the solution was concentrated under reduced pressure and purified by column chromatography.

References:

Li, Bai;Gao, Linfeng;Bian, Fengling;Yu, Wei [Tetrahedron Letters,2013,vol. 54,# 9,p. 1063 - 1066] Location in patent:supporting information

FullText

108-38-3
367 suppliers
$10.60/50gm:

583-70-0
238 suppliers
$15.00/5mg

620-13-3 Synthesis