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ChemicalBook CAS DataBase List 1H,1H,2H,2H-Perfluorohexyl iodide
2043-55-2

1H,1H,2H,2H-Perfluorohexyl iodide synthesis

2synthesis methods
-

Yield:2043-55-2 85.3 kg

Reaction Conditions:

with 2,2'-azobis(isobutyronitrile) in isopropyl alcohol at 60 - 70; under 3375.34 Torr; for 3.5 h;Large scale;Green chemistry;Solvent;Temperature;Pressure;

Steps:

1.1; 1; 3.1; 5 Example 3:

(1) In a 100 liter pressure stainless steel reaction kettle, first add 500 g of azobisisovaleronitrile, and then vacuum inhale 80 kg of perfluoroiodobutane 80 kg and 16 kg of isopropyl alcohol, and stir to raise the temperature to 60 ° C. , slowly introduce ethylene to a pressure of 0.45MPa, holdingContinued temperature 65~70 °C reaction for 3.5 hours, the pressure no longer has a significant drop. The heating was removed, and the discharge was followed by distillation to remove isopropanol to obtain 85.3 kg of a 99% purity: C4F9CH2CH2I.

References:

CN108911983,2018,A Location in patent:Paragraph 0018; 0021; 0028; 0031

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