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ChemicalBook CAS DataBase List 1-Octen-3-one
4312-99-6

1-Octen-3-one synthesis

12synthesis methods
-

Yield:4312-99-6 100%

Reaction Conditions:

with cis-dichlorotetrakis(diemethylsulfoxide) ruthenium(II);sodium formate in water;toluene at 80; for 1 h;Inert atmosphere;

Steps:

4.5 General procedure for catalytic isomerization of allylic alcohols

General procedure: Under an inert atmosphere, the catalyst precursor (0.01 mmol) and Na-formate (0.5 mmol) were dissolved in 3 mL of deoxygenated water. The solution was then heated to the indicated temperature and then allylic alcohol (0.5 mmol, in 1 mL of toluene) was introduced. The system was rapidly stirred for 1 h and then was cooled to room temperature. The separated organic phase was filtered through a short silica gel column and was subjected to gas chromatography.

References:

Udvardy, Antal;Bényei, Attila Csaba;Kathó, ágnes [Journal of Organometallic Chemistry,2012,vol. 717,p. 116 - 122]

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