1-(4-Bromophenyl)piperazine synthesis
- Product Name:1-(4-Bromophenyl)piperazine
- CAS Number:66698-28-0
- Molecular formula:C10H13BrN2
- Molecular Weight:241.13
92-54-6
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66698-28-0
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$10.00/250mg
Yield:66698-28-0 96%
Reaction Conditions:
with hydrogen bromide;dimethyl sulfoxide at 60; for 2 h;
Steps:
Synthesis of bromination products: general procedure
General procedure: In a round-bottomed flask, the substrate (1 mmol) and aqueous HBr(48%) (1 mL) were mixed in DMSO (1 mL). The mixture was stirredat corresponding temperature for 1-4 h. After cooling to roomtemperature, the reaction was adjusted to pH 7-8 with aqueous NaOHsolution (4 M). Then the mixture was washed twice with EtOAc, andthe combined organic extracts were dried, filtered and concentratedunder reduced pressure to give bromination products.
References:
Liu, Cong;Dai, Rongji;Yao, Guowei;Deng, Yulin [Journal of Chemical Research,2014,vol. 38,# 10,p. 593 - 596]
821-48-7
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106-40-1
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66698-28-0
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110-85-0
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106-37-6
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66698-28-0
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352437-09-3
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66698-28-0
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334-22-5
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106-40-1
469 suppliers
$12.00/5g
66698-28-0
142 suppliers
$10.00/250mg