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ChemicalBook >> CAS DataBase List >> Vorapaxar Sulfate

Vorapaxar Sulfate

Vorapaxar Sulfate price.
  • $456 - $1900
  • Product name: Vorapaxar Sulfate
  • CAS: 705260-08-8
  • MF: C29H35FN2O8S
  • MW: 590.66
  • EINECS:
  • MDL Number:MFCD16038877
  • Synonyms:Vorapaxar Sulfate;N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-Fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-Methyl-3-oxonaphtho[2,3-c]furan-6-yl]carbaMic Acid Ethyl Ester Sulfate;Sch 530348;SCH 530348 (H2SO4 Salt);vorapaxar impurity A;Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester, sulfate (1:1);SCH-530348;SCH530348;Vorapaxar Sulfate (SCH 530348)
8 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • Chemenu
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 5MG
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0014130
  • Product descriptionSCH-530348 SULPHATE 95.00%
  • Packaging5MG
  • Price$500.42
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM140098
  • Product descriptionethyl((1R,3aR,4aR,6R,8aR,9S,9aS)-9-((E)-2-(5-(3-fluorophenyl)pyridin-2-yl)vinyl)-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl)carbamatesulfate 97%
  • Packaging1g
  • Price$1066
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11069485
  • Product descriptionVorapaxarSulfate 97%
  • Packaging250mg
  • Price$456
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11069485
  • Product descriptionVorapaxarSulfate 97%
  • Packaging1g
  • Price$1140
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8229
  • Product descriptionVorapaxarSulfate(SCH530348) >98%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8229
  • Product descriptionVorapaxarSulfate(SCH530348) >98%
  • Packaging250mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8229
  • Product descriptionVorapaxarSulfate(SCH530348) >98%
  • Packaging1g
  • Price$1900
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberV758200
  • Product descriptionVorapaxarSulfate
  • Packaging100mg
  • Price$580
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0014130 SCH-530348 SULPHATE 95.00% 5MG $500.42 2021-12-16 Buy
Chemenu CM140098 ethyl((1R,3aR,4aR,6R,8aR,9S,9aS)-9-((E)-2-(5-(3-fluorophenyl)pyridin-2-yl)vinyl)-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl)carbamatesulfate 97% 1g $1066 2021-12-16 Buy
Crysdot CD11069485 VorapaxarSulfate 97% 250mg $456 2021-12-16 Buy
Crysdot CD11069485 VorapaxarSulfate 97% 1g $1140 2021-12-16 Buy
DC Chemicals DC8229 VorapaxarSulfate(SCH530348) >98% 100mg $550 2021-12-16 Buy
DC Chemicals DC8229 VorapaxarSulfate(SCH530348) >98% 250mg $950 2021-12-16 Buy
DC Chemicals DC8229 VorapaxarSulfate(SCH530348) >98% 1g $1900 2021-12-16 Buy
TRC V758200 VorapaxarSulfate 100mg $580 2021-12-16 Buy

Properties

storage temp. :4°C, away from moisture
solubility :DMSO : 125 mg/mL (211.63 mM; Need ultrasonic)| (insoluble)
form :Solid
color :White to off-white
Water Solubility :Water : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warning P264, P305+P351+P338,P337+P313
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Merck Sharp & Dohme successfully obtained approval in the EU in 2014 for vorapaxar sulfate, marketed as Zontivity®. The drug is a first-in-class thrombin receptor (also referred to as a protease-activated or PAR-1) antagonist which, when used in conjunction with antiplatelet therapy, has been shown to reduce the chance of myocardial infarction and stroke, particularly in patients with a history of cardiac events. Antagonism of PAR-1 allows for thrombin-mediated fibrin deposition while blocking thrombinmediated platelet activation.

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