99% purity available from supplier Axon Medchem, prime source of life science reagents for your research" />

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BI 6727 - Volasertib

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1473

CAS [755038-65-4]

MF C34H50N8O3
MW 618.81

  • Purity: 99%
  • Optical purity: Optically pure
  • Moderately soluble in DMSO

BI 6727

Description

A highly potent and selective polo-like kinase (PLK) 1 inhibitor (enzyme IC50 = 0.87 nM, EC50 = 11-37 nM on a panel of cancer cell lines), which exhibited significant anti-proliferative in multiple cancer models, including a model of taxane-resistant colorectal cancer. A high volume of distribution, indicating good tissue penetration, and a long terminal half-life have emerged as distinct features of BI 6727, which may have a favorable effect on antitumor efficacy in vivo.
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2 mg $99.00 In Stock
5 mg $137.50 In Stock
25 mg $478.50 In Stock
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2 x 5 mg $198.00 In Stock
2 x 25 mg $704.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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