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ChemicalBook >> CAS DataBase List >> URMC-099

URMC-099

URMC-099 price.
  • $29 - $1782
  • Product name: URMC-099
  • CAS: 1229582-33-5
  • MF: C27H27N5
  • MW: 421.54
  • EINECS:
  • MDL Number:MFCD28168077
  • Synonyms:3-(1H-indol-5-yl)-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridine URMC-099;URMC-099;3-(1H-indol-5-yl)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridine;1H-?Pyrrolo[2,?3-?b]?pyridine, 3-?(1H-?indol-?5-?yl)?-?5-?[4-?[(4-?methyl-?1-?piperazinyl)?methyl]?phenyl]?-;CS-1776;URMC-099;URMC 099;RMC099;inhibit,MLKs,Autophagy,URMC 099,URMC099,URMC-099,Inhibitor,Mixed Lineage Kinase
22 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 5mg
  • 25mg
  • 50mg
  • 10mM(in 1mL DMSO)
  • 1mg
  • 10mg
  • 100mg
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1211-M005
  • Product descriptionURMC-099 ≥95%(HPLC)
  • Packaging5mg
  • Price$194
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1211-M100
  • Product descriptionURMC-099 ≥95%(HPLC)
  • Packaging100mg
  • Price$1782
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX3562
  • Product descriptionURMC-099
  • Packaging10mg
  • Price$172
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1211
  • Product descriptionURMC-099
  • Packaging5mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4877
  • Product descriptionURMC-099
  • Packaging5mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4877
  • Product descriptionURMC-099
  • Packaging10mM(in 1mL DMSO)
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4877
  • Product descriptionURMC-099
  • Packaging25mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4877
  • Product descriptionURMC-099
  • Packaging100mg
  • Price$720
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFU170951
  • Product descriptionURMC 099
  • Packaging50mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFU170951
  • Product descriptionURMC 099
  • Packaging100mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19147
  • Product descriptionURMC-099 ≥95%
  • Packaging1mg
  • Price$29
  • Updated2022-04-27
  • Buy
  • ManufacturerCayman Chemical
  • Product number19147
  • Product descriptionURMC-099 ≥95%
  • Packaging5mg
  • Price$60
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19147
  • Product descriptionURMC-099 ≥95%
  • Packaging10mg
  • Price$99
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19147
  • Product descriptionURMC-099 ≥95%
  • Packaging25mg
  • Price$162
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM148925
  • Product description3-(1H-indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 95%+
  • Packaging10mg
  • Price$211
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4182
  • Product descriptionURMC-099 99.90%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1211-M005 URMC-099 ≥95%(HPLC) 5mg $194 2021-12-16 Buy
Adipogen Life Sciences SYN-1211-M100 URMC-099 ≥95%(HPLC) 100mg $1782 2021-12-16 Buy
AK Scientific X3562 URMC-099 10mg $172 2021-12-16 Buy
AK Scientific SYN1211 URMC-099 5mg $200 2021-12-16 Buy
ApexBio Technology B4877 URMC-099 5mg $95 2021-12-16 Buy
ApexBio Technology B4877 URMC-099 10mM(in 1mL DMSO) $132 2021-12-16 Buy
ApexBio Technology B4877 URMC-099 25mg $280 2021-12-16 Buy
ApexBio Technology B4877 URMC-099 100mg $720 2021-12-16 Buy
Biosynth Carbosynth FU170951 URMC 099 50mg $250 2021-12-16 Buy
Biosynth Carbosynth FU170951 URMC 099 100mg $400 2021-12-16 Buy
Cayman Chemical 19147 URMC-099 ≥95% 1mg $29 2022-04-27 Buy
Cayman Chemical 19147 URMC-099 ≥95% 5mg $60 2024-03-01 Buy
Cayman Chemical 19147 URMC-099 ≥95% 10mg $99 2024-03-01 Buy
Cayman Chemical 19147 URMC-099 ≥95% 25mg $162 2024-03-01 Buy
Chemenu CM148925 3-(1H-indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 95%+ 10mg $211 2021-12-16 Buy
ChemScene CS-4182 URMC-099 99.90% 5mg $60 2021-12-16 Buy

Properties

Density :1.256±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :solid
pka :13.49±0.40(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

URMC-099 is an orally bioavailable, brain-penetrant inhibitor of mixed-lineage kinases (MLKs) with IC50 values of 19, 42, 14, and 150 nM for MLK1, MLK2, MLK3, and the related MLK family member DLK, respectively. It also inhibits LRRK2 activity with an IC50 value of 11 nM. In vitro, URMC-099 has been shown to reduce inflammatory cytokine production by HIV-1 Tat-exposed microglia and to prevent destruction and phagocytosis of cultured neuronal axons by these cells. In rodent models of HIV-associated neurocognitive disorders, URMC-099 demonstrates anti-inflammatory and neuroprotective effects.

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