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      ChemicalBook >> CAS DataBase List >> T0070907

      T0070907

      T0070907 price.
      • $6 - $1593.9
      • Product name: T0070907
      • CAS: 313516-66-4
      • MF: C12H8ClN3O3
      • MW: 277.66
      • EINECS:
      • MDL Number:MFCD00121849
      • Synonyms:2-CHLORO-5-NITRO-N-4-PYRIDINYLBENZAMIDE;2-CHLORO-5-NITRO-N-(4-PYRIDYL)BENZAMIDE;T 0070907;N1-(4-PYRIDYL)-2-CHLORO-5-NITROBENZAMIDE;BenzaMide, 2-chloro-5-nitro-N-4-pyridinyl-;T0070907 - CAS 313516-66-4 - Calbiochem;CS-2314;T0070907 (T-0070907
      44 prices
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      Brand
      • Abosyn
      • AK Scientific
      • Alfa Aesar
      • Ambeed
      • American Custom Chemicals Corporation
      • ApexBio Technology
      • Arctom
      • Biosynth Carbosynth
      • Cayman Chemical
      • Chemenu
      • ChemScene
      • DC Chemicals
      • Matrix Scientific
      • Oakwood
      • Sigma-Aldrich
      • SynQuest Laboratories
      • Tocris
      • TRC
      • Usbiological
      Package
      • 25
      • 5mg
      • 1mg
      • 5
      • 10mg
      • 20mg
      • 25mg
      • 50mg
      • 100mg
      • 250mg
      • 1g
      • 10mM(in 1mL DMSO)
      • ManufacturerAbosyn
      • Product number61-5075
      • Product description2-chloro-5-nitro-N-(pyridin-4-yl)benzamide 95+%
      • Packaging1g
      • Price$405
      • Updated2021-12-16
      • Buy
      • ManufacturerAK Scientific
      • Product numberW5337
      • Product description2-Chloro-5-nitro-N-4-pyridinylbenzamide
      • Packaging100mg
      • Price$151
      • Updated2021-12-16
      • Buy
      • ManufacturerAK Scientific
      • Product numberW5337
      • Product description2-Chloro-5-nitro-N-4-pyridinylbenzamide
      • Packaging250mg
      • Price$198
      • Updated2021-12-16
      • Buy
      • ManufacturerAlfa Aesar
      • Product numberJ64455
      • Product description2-Chloro-5-nitro-N-(4-pyridyl)benzamide
      • Packaging10mg
      • Price$118
      • Updated2021-12-16
      • Buy
      • ManufacturerAlfa Aesar
      • Product numberJ64455
      • Product description2-Chloro-5-nitro-N-(4-pyridyl)benzamide
      • Packaging50mg
      • Price$444
      • Updated2021-12-16
      • Buy
      • ManufacturerAmbeed
      • Product numberA227971
      • Product descriptionT0070907 98+%
      • Packaging5mg
      • Price$6
      • Updated2021-12-16
      • Buy
      • ManufacturerAmbeed
      • Product numberA227971
      • Product descriptionT0070907 98+%
      • Packaging10mg
      • Price$9
      • Updated2021-12-16
      • Buy
      • ManufacturerAmbeed
      • Product numberA227971
      • Product descriptionT0070907 98+%
      • Packaging25mg
      • Price$15
      • Updated2021-12-16
      • Buy
      • ManufacturerAmbeed
      • Product numberA227971
      • Product descriptionT0070907 98+%
      • Packaging50mg
      • Price$22
      • Updated2021-12-16
      • Buy
      • ManufacturerAmbeed
      • Product numberA227971
      • Product descriptionT0070907 98+%
      • Packaging100mg
      • Price$33
      • Updated2021-12-16
      • Buy
      • ManufacturerAmbeed
      • Product numberA227971
      • Product descriptionT0070907 98+%
      • Packaging250mg
      • Price$57
      • Updated2021-12-16
      • Buy
      • ManufacturerAmbeed
      • Product numberA227971
      • Product descriptionT0070907 98+%
      • Packaging1g
      • Price$155
      • Updated2021-12-16
      • Buy
      • ManufacturerAmerican Custom Chemicals Corporation
      • Product numberINB0004411
      • Product description2-CHLORO-5-NITRO-N-4-PYRIDINYLBENZAMIDE 95.00%
      • Packaging10MG
      • Price$704.55
      • Updated2021-12-16
      • Buy
      • ManufacturerAmerican Custom Chemicals Corporation
      • Product numberINB0004411
      • Product description2-CHLORO-5-NITRO-N-4-PYRIDINYLBENZAMIDE 95.00%
      • Packaging100MG
      • Price$1593.9
      • Updated2021-12-16
      • Buy
      • ManufacturerApexBio Technology
      • Product numberA4301
      • Product descriptionT0070907
      • Packaging50mg
      • Price$190
      • Updated2021-12-16
      • Buy
      • ManufacturerApexBio Technology
      • Product numberA4301
      • Product descriptionT0070907
      • Packaging25mg
      • Price$120
      • Updated2021-12-16
      • Buy
      Manufacturer Product number Product description Packaging Price Updated Buy
      Abosyn 61-5075 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide 95+% 1g $405 2021-12-16 Buy
      AK Scientific W5337 2-Chloro-5-nitro-N-4-pyridinylbenzamide 100mg $151 2021-12-16 Buy
      AK Scientific W5337 2-Chloro-5-nitro-N-4-pyridinylbenzamide 250mg $198 2021-12-16 Buy
      Alfa Aesar J64455 2-Chloro-5-nitro-N-(4-pyridyl)benzamide 10mg $118 2021-12-16 Buy
      Alfa Aesar J64455 2-Chloro-5-nitro-N-(4-pyridyl)benzamide 50mg $444 2021-12-16 Buy
      Ambeed A227971 T0070907 98+% 5mg $6 2021-12-16 Buy
      Ambeed A227971 T0070907 98+% 10mg $9 2021-12-16 Buy
      Ambeed A227971 T0070907 98+% 25mg $15 2021-12-16 Buy
      Ambeed A227971 T0070907 98+% 50mg $22 2021-12-16 Buy
      Ambeed A227971 T0070907 98+% 100mg $33 2021-12-16 Buy
      Ambeed A227971 T0070907 98+% 250mg $57 2021-12-16 Buy
      Ambeed A227971 T0070907 98+% 1g $155 2021-12-16 Buy
      American Custom Chemicals Corporation INB0004411 2-CHLORO-5-NITRO-N-4-PYRIDINYLBENZAMIDE 95.00% 10MG $704.55 2021-12-16 Buy
      American Custom Chemicals Corporation INB0004411 2-CHLORO-5-NITRO-N-4-PYRIDINYLBENZAMIDE 95.00% 100MG $1593.9 2021-12-16 Buy
      ApexBio Technology A4301 T0070907 50mg $190 2021-12-16 Buy
      ApexBio Technology A4301 T0070907 25mg $120 2021-12-16 Buy

      Properties

      Melting point :>184°C (dec.)
      Density :1.498
      storage temp. :2-8°C
      solubility :DMSO: >10mg/mL
      form :White solid
      color :white
      Water Solubility :Soluble in DMSO at 10mg/ml. Insoluble in water.
      Sensitive :Light Sensitive

      Safety Information

      Symbol(GHS): GHS hazard pictograms
      Signal word: Warning
      Hazard statements:
      Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
      H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
      H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
      H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
      H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
      Precautionary statements:
      P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
      P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
      P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
      P405 Store locked up.

      Description

      The peroxisome proliferator-activated receptor-γ (PPARγ) is the nuclear receptor responsible for transducing the therapeutic activity of the thiazolidinediones (TZDs). TZDs are a group of structurally related synthetic PPARγ receptor agonists with antidiabetic actions in vivo. There are many PPARγ agonists, including 15-deoxy-Δ12,14-prostaglandin J2 and azelaoyl PAF, which are naturally derived. However, only a few antagonists have been reported. T0070907 is a potent and selective antagonist of the human PPARγ with an apparent IC50 of 1 nM for the binding inhibition of rosiglitazone, a reference TZD. T0070907 covalently binds to Cys313 of PPARγ, inducing conformational changes that block the recruitment of transcriptional cofactors to the PPARγ/RXR heterodimer.

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