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ChemicalBook >> CAS DataBase List >> Rosiglitazone maleate

Rosiglitazone maleate

Rosiglitazone maleate price.
  • $5 - $1504.5
  • Product name: Rosiglitazone maleate
  • CAS: 155141-29-0
  • MF: C22H23N3O7S
  • MW: 473.5
  • EINECS:642-163-6
  • MDL Number:MFCD03427306
  • Synonyms:5-((4-[2-(METHYL-2-PYRIDINYLAMINO)-ETHOXY]-PHENYL)-METHYLENE)-2,4-THIAZOLIDINEDIONE;5-{p-[2-(methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedione maleate;ROSIGLITAZONE MALEATE;RosiglitazoneTartrate;Avandi;BRL-49653c;RSIGLITAZONEMALEATE;5-(4-(2-(Methyl(pyridin-2-yl)aMino)ethoxy)benzyl)thiazolidine-2,4-dione Maleate
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Brand
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemcia Scientific
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 10mg
  • 25MG
  • 5MG
  • 10mM(in 1mL DMSO)
  • 50mg
  • 0.1g
  • 100mg
  • 200mg
  • 250mg
  • 300MG
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  • 1g
  • 5g
  • 10g
  • 25g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3571-G001
  • Product descriptionRosiglitazone maleate ≥98%(NMR)
  • Packaging1g
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-22200
  • Product descriptionRosiglitazone maleate 98%
  • Packaging5g
  • Price$310
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberH694
  • Product descriptionRosiglitazone maleate
  • Packaging100mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ11270
  • Product descriptionRosiglitazone maleate
  • Packaging1g
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA332359
  • Product descriptionRosiglitazone maleate 98+%
  • Packaging10mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA332359
  • Product descriptionRosiglitazone maleate 98+%
  • Packaging50mg
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA332359
  • Product descriptionRosiglitazone maleate 98+%
  • Packaging100mg
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA332359
  • Product descriptionRosiglitazone maleate 98+%
  • Packaging250mg
  • Price$16
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA332359
  • Product descriptionRosiglitazone maleate 98+%
  • Packaging1g
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA332359
  • Product descriptionRosiglitazone maleate 98+%
  • Packaging5g
  • Price$113
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA332359
  • Product descriptionRosiglitazone maleate 98+%
  • Packaging10g
  • Price$177
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004101
  • Product descriptionROSIGLITAZONE MALEATE 95.00%
  • Packaging5MG
  • Price$515
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004101
  • Product descriptionROSIGLITAZONE MALEATE 95.00%
  • Packaging25MG
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004101
  • Product descriptionROSIGLITAZONE MALEATE 95.00%
  • Packaging100MG
  • Price$670
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004101
  • Product descriptionROSIGLITAZONE MALEATE 95.00%
  • Packaging250MG
  • Price$790
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4302
  • Product descriptionRosiglitazone maleate
  • Packaging25mg
  • Price$50
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3571-G001 Rosiglitazone maleate ≥98%(NMR) 1g $180 2021-12-16 Buy
AHH MT-22200 Rosiglitazone maleate 98% 5g $310 2021-12-16 Buy
AK Scientific H694 Rosiglitazone maleate 100mg $35 2021-12-16 Buy
AK Scientific J11270 Rosiglitazone maleate 1g $218 2021-12-16 Buy
Ambeed A332359 Rosiglitazone maleate 98+% 10mg $5 2021-12-16 Buy
Ambeed A332359 Rosiglitazone maleate 98+% 50mg $6 2021-12-16 Buy
Ambeed A332359 Rosiglitazone maleate 98+% 100mg $11 2021-12-16 Buy
Ambeed A332359 Rosiglitazone maleate 98+% 250mg $16 2021-12-16 Buy
Ambeed A332359 Rosiglitazone maleate 98+% 1g $39 2021-12-16 Buy
Ambeed A332359 Rosiglitazone maleate 98+% 5g $113 2021-12-16 Buy
Ambeed A332359 Rosiglitazone maleate 98+% 10g $177 2021-12-16 Buy
American Custom Chemicals Corporation API0004101 ROSIGLITAZONE MALEATE 95.00% 5MG $515 2021-12-16 Buy
American Custom Chemicals Corporation API0004101 ROSIGLITAZONE MALEATE 95.00% 25MG $550 2021-12-16 Buy
American Custom Chemicals Corporation API0004101 ROSIGLITAZONE MALEATE 95.00% 100MG $670 2021-12-16 Buy
American Custom Chemicals Corporation API0004101 ROSIGLITAZONE MALEATE 95.00% 250MG $790 2021-12-16 Buy
ApexBio Technology A4302 Rosiglitazone maleate 25mg $50 2021-12-16 Buy

Properties

Melting point :235-240°C
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 50 mg/ml).
pka :6.1; 6.8(at 25℃)
form :White powder
color :White
BCS Class :1
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months
InChIKey :HCDYSWMAMRPMST-NTCAYCPXSA-N
CAS DataBase Reference :155141-29-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Thiazolidinediones (TZDs) are a group of structurally related peroxisome proliferator-activated receptor γ (PPARγ) agonists with antidiabetic actions in vivo. Rosiglitazone is a prototypical TZD that has served as a reference compound for this class. It is a potent and selective PPARγ ligand that binds to the PPARγ ligand-binding domain with a Kd value of 43 nM. It activates luciferase-based expression constructs PPARγ1 and PPARγ2 with EC50 values of approximately 30 nM and 100 nM, respectively. Rosiglitazone is active in vivo as an antidiabetic agent in the ob/ob mouse model, and has been used as an oral hypoglycemic agent in the treatment of type 2 diabetes in humans for many years.

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