Selonsertib
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- $32 - $1609
- Product name: Selonsertib
- CAS: 1448428-04-3
- MF: C24H24FN7O
- MW: 445.49
- EINECS:
- MDL Number:MFCD29920355
- Synonyms:Selonsertib;5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide;Selonsertib GS-4997;GS-4497;GS-4997;ASK-1;GS4997 SELONSERTIB;5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide;Benzamide, 5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]-
32 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Ark Pharm
- Axon Medchem
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 500μg
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1231-M005
- Product descriptionSelonsertib(freebase) ≥95%
- Packaging5mg
- Price$205
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1231-M010
- Product descriptionSelonsertib(freebase) ≥95%
- Packaging10mg
- Price$313
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1231-M100
- Product descriptionSelonsertib(freebase) ≥95%
- Packaging100mg
- Price$1609
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN1231
- Product descriptionSelonsertib
- Packaging100mg
- Price$1510
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004753
- Product description5-(4-CYCLOPROPYL-1H-IMIDAZOL-1-YL)-2-FLUORO-4-METHYL-N-[6-[4-(1-METHYLETHYL)-4H-1,2,4-TRIAZOL-3-YL]-2-PYRIDINYL]-BENZAMIDE 95.00%
- Packaging5MG
- Price$497.89
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7812
- Product descriptionSelonsertib(GS-4997)
- Packaging5mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7812
- Product descriptionSelonsertib(GS-4997)
- Packaging25mg
- Price$208
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7812
- Product descriptionSelonsertib(GS-4997)
- Packaging100mg
- Price$474
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000132047
- Product descriptionSelonsertib 97%
- Packaging1mg
- Price$63
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000132047
- Product descriptionSelonsertib 97%
- Packaging5mg
- Price$86
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000132047
- Product descriptionSelonsertib 97%
- Packaging10mg
- Price$156
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000132047
- Product descriptionSelonsertib 97%
- Packaging50mg
- Price$469
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000132047
- Product descriptionSelonsertib 97%
- Packaging100mg
- Price$688
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000132047
- Product descriptionSelonsertib 97%
- Packaging250mg
- Price$1156
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2956
- Product descriptionSelonsertib-GS4997 99%
- Packaging10mg
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC157241
- Product descriptionSelonsertib
- Packaging10mg
- Price$90
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-1231-M005 | Selonsertib(freebase) ≥95% | 5mg | $205 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1231-M010 | Selonsertib(freebase) ≥95% | 10mg | $313 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1231-M100 | Selonsertib(freebase) ≥95% | 100mg | $1609 | 2021-12-16 | Buy |
| AK Scientific | SYN1231 | Selonsertib | 100mg | $1510 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004753 | 5-(4-CYCLOPROPYL-1H-IMIDAZOL-1-YL)-2-FLUORO-4-METHYL-N-[6-[4-(1-METHYLETHYL)-4H-1,2,4-TRIAZOL-3-YL]-2-PYRIDINYL]-BENZAMIDE 95.00% | 5MG | $497.89 | 2021-12-16 | Buy |
| ApexBio Technology | B7812 | Selonsertib(GS-4997) | 5mg | $68 | 2021-12-16 | Buy |
| ApexBio Technology | B7812 | Selonsertib(GS-4997) | 25mg | $208 | 2021-12-16 | Buy |
| ApexBio Technology | B7812 | Selonsertib(GS-4997) | 100mg | $474 | 2021-12-16 | Buy |
| Ark Pharm | P000132047 | Selonsertib 97% | 1mg | $63 | 2021-12-16 | Buy |
| Ark Pharm | P000132047 | Selonsertib 97% | 5mg | $86 | 2021-12-16 | Buy |
| Ark Pharm | P000132047 | Selonsertib 97% | 10mg | $156 | 2021-12-16 | Buy |
| Ark Pharm | P000132047 | Selonsertib 97% | 50mg | $469 | 2021-12-16 | Buy |
| Ark Pharm | P000132047 | Selonsertib 97% | 100mg | $688 | 2021-12-16 | Buy |
| Ark Pharm | P000132047 | Selonsertib 97% | 250mg | $1156 | 2021-12-16 | Buy |
| Axon Medchem | Axon2956 | Selonsertib-GS4997 99% | 10mg | $99 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC157241 | Selonsertib | 10mg | $90 | 2021-12-16 | Buy |
Properties
Melting point :>180°C (dec.)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
pka :11.21±0.70(Predicted)
form :solid
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :YIDDLAAKOYYGJG-UHFFFAOYSA-N
SMILES :C(NC1=NC(C2N(C(C)C)C=NN=2)=CC=C1)(=O)C1=CC(N2C=NC(C3CC3)=C2)=C(C)C=C1F
CAS DataBase Reference :1448428-04-3
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
pka :11.21±0.70(Predicted)
form :solid
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :YIDDLAAKOYYGJG-UHFFFAOYSA-N
SMILES :C(NC1=NC(C2N(C(C)C)C=NN=2)=CC=C1)(=O)C1=CC(N2C=NC(C3CC3)=C2)=C(C)C=C1F
CAS DataBase Reference :1448428-04-3
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Selonsertib (1448428-04-3) is a potent Apoptosis signal-regulating kinase 1 (ASK1) inhibitor (pIC50 = 8.3)1 found to improve metabolic parameters in nonalcoholic steatohepatitis, reduce hepatic steatosis, inflammation, and fibrosis2-4. Selonsertib suppressed the efflux function of multidrug resistance (MDR) transporters ABCB1 and ABCG2.5Related product price
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