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ChemicalBook >> CAS DataBase List >> 4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE

4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE

4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE price.
  • $15 - $2004
  • Product name: 4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE
  • CAS: 101574-65-6
  • MF: C17H18N2O2
  • MW: 282.34
  • EINECS:
  • MDL Number:MFCD00567155
  • Synonyms:(E)-4-hydroxy-N'-(4-isopropylbenzylidene)benzohydrazide;4-Hydroxybenzoic acid 2-[[4-(1-methylethyl)phenyl]methylene]hydrazide;4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE;2-[[4-(1-Methylethyl)phenyl]methylene]hydrazide 4-hydroxybenzoic acid;4-hydroxy-N'-(4-isopropylbenzylidene)benzohydrazide;CS-1084;Benzoic acid, 4-hydroxy-, 2-[[4-(1-methylethyl)phenyl]methylene]hydrazide;4-hydroxy-N'-(4-isopropylphenyl‐ methylidene)-benzohydrazide
26 prices
Selected condition：
Brand
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Aronis compounds
  • Biosynth Carbosynth
  • Cayman Chemical
  • Crysdot
  • CSNpharm
  • Sigma-Aldrich
  • TRC
Package
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2690BB
  • Product description4-Hydroxy-N-[(E)-(4-propan-2-ylphenyl)methylideneamino]benzamide
  • Packaging1g
  • Price$2004
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ65166
  • Product descriptionGSK 4716
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ65166
  • Product descriptionGSK 4716
  • Packaging50mg
  • Price$248
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA262201
  • Product descriptionGSK 4716 98%
  • Packaging10mg
  • Price$89
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA262201
  • Product descriptionGSK 4716 98%
  • Packaging25mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA262201
  • Product descriptionGSK 4716 98%
  • Packaging50mg
  • Price$186
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA262201
  • Product descriptionGSK 4716 98%
  • Packaging100mg
  • Price$279
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0000397
  • Product descriptionGSK 4716 95.00%
  • Packaging50MG
  • Price$625
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0000397
  • Product descriptionGSK 4716 95.00%
  • Packaging10MG
  • Price$485
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0000397
  • Product descriptionGSK 4716 95.00%
  • Packaging5MG
  • Price$465
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7265
  • Product descriptionGSK 4716
  • Packaging10mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7265
  • Product descriptionGSK 4716
  • Packaging50mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerAronis compounds
  • Product numberM0752
  • Product description4-hydroxy-N'-(4-isopropylbenzylidene)benzohydrazide
  • Packaging5mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAronis compounds
  • Product numberM0752
  • Product description4-hydroxy-N'-(4-isopropylbenzylidene)benzohydrazide
  • Packaging50mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFG167327
  • Product descriptionGSK 4716
  • Packaging10mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFG167327
  • Product descriptionGSK 4716
  • Packaging50mg
  • Price$227.5
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2690BB 4-Hydroxy-N-[(E)-(4-propan-2-ylphenyl)methylideneamino]benzamide 1g $2004 2021-12-16 Buy
Alfa Aesar J65166 GSK 4716 10mg $70 2021-12-16 Buy
Alfa Aesar J65166 GSK 4716 50mg $248 2021-12-16 Buy
Ambeed A262201 GSK 4716 98% 10mg $89 2021-12-16 Buy
Ambeed A262201 GSK 4716 98% 25mg $133 2021-12-16 Buy
Ambeed A262201 GSK 4716 98% 50mg $186 2021-12-16 Buy
Ambeed A262201 GSK 4716 98% 100mg $279 2021-12-16 Buy
American Custom Chemicals Corporation SHG0000397 GSK 4716 95.00% 50MG $625 2021-12-16 Buy
American Custom Chemicals Corporation SHG0000397 GSK 4716 95.00% 10MG $485 2021-12-16 Buy
American Custom Chemicals Corporation SHG0000397 GSK 4716 95.00% 5MG $465 2021-12-16 Buy
ApexBio Technology B7265 GSK 4716 10mg $65 2021-12-16 Buy
ApexBio Technology B7265 GSK 4716 50mg $280 2021-12-16 Buy
Aronis compounds M0752 4-hydroxy-N'-(4-isopropylbenzylidene)benzohydrazide 5mg $15 2021-12-16 Buy
Aronis compounds M0752 4-hydroxy-N'-(4-isopropylbenzylidene)benzohydrazide 50mg $50 2021-12-16 Buy
Biosynth Carbosynth FG167327 GSK 4716 10mg $65 2021-12-16 Buy
Biosynth Carbosynth FG167327 GSK 4716 50mg $227.5 2021-12-16 Buy

Properties

Density :1.12
storage temp. :Inert atmosphere,2-8°C
solubility :DMSO: >10mg/mL
form :powder
pka :8.48±0.15(Predicted)
color :white to off-white

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.

Description

The estrogen-related receptors (ERRs) are orphan nuclear receptors with homology to the estrogen receptor family and are expressed in tissues with high metabolic demand. Binding of peroxisome proliferator-activated receptor γ-coactivator 1α (PGC-1α) to this class of receptors is known to potentiate ERR activity. GSK4716 is an ERRβ/γ agonist (IC50 = 2 μM) that can activate the receptor with similar potency as the protein ligand, PGC-1α. It is more than 50-fold selective for binding to ERRβ/γ compared with the estrogen receptors. This compound has been used to demonstrate the contribution of ERR receptor activity to the regulation of mitochondrial activity in skeletal muscle during exercise.

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