Rosiglitazone maleate
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1G |
| Supply Ability: | 100KG |
| Update Time: | 2019-07-06 |
Product Details
| Product Name: Rosiglitazone maleate | CAS No.: 155141-29-0 |
| Min. Order: 1G | Purity: 98% |
| Supply Ability: 100KG | Release date: 2019/07/06 |
AD68
| Rosiglitazone maleate Basic information |
| Product Name: | Rosiglitazone maleate |
| Synonyms: | 5-((4-[2-(METHYL-2-PYRIDINYLAMINO)-ETHOXY]-PHENYL)-METHYLENE)-2,4-THIAZOLIDINEDIONE;5-{p-[2-(methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedione maleate;ROSIGLITAZONE MALEATE;RosiglitazoneTartrate;Avandi;BRL-49653c;RSIGLITAZONEMALEATE;5-(4-(2-(Methyl(pyridin-2-yl)aMino)ethoxy)benzyl)thiazolidine-2,4-dione Maleate |
| CAS: | 155141-29-0 |
| MF: | C22H23N3O7S |
| MW: | 473.5 |
| EINECS: | 1312995-182-4 |
| Product Categories: | Active Pharmaceutical Ingredients;Antidiabetic;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Rosiglitazone;Heterocycles;Sulfur & Selenium Compounds;Inhibitor;API |
| Mol File: | 155141-29-0.mol |
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| Rosiglitazone maleate Chemical Properties |
| Melting point | 235-240°C |
| storage temp. | -20°C Freezer |
| pka | 6.1; 6.8(at 25℃) |
| CAS DataBase Reference | 155141-29-0(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 20/21/22-36/38 |
| Safety Statements | 24/25-37/39-26 |
| MSDS Information |
| Rosiglitazone maleate Usage And Synthesis |
| Chemical Properties | White To Off-White Solid |
| Uses | Insulin sensitizer; binds to peroxisome proliferator activated receptor gamma (PPAR- γ). |
| Uses | Thiazole alkanes antidiabetic drug |
| Uses | Thiazolidinediones (TZDs) are a group of structurally related peroxisome proliferator-activated receptor γ (PPARγ) agonists with antidiabetic actions in vivo. Rosiglitazone is a prototypical TZD that has served as a reference compound for this class. It is a potent and selective PPARγ ligand that binds to the PPARγ ligand-binding domain with a Kd value of 43 nM. It activates luciferase-based expression constructs PPARγ1 and PPARγ2 with EC50 values of approximately 30 nM and 100 nM, respectively. Rosiglitazone is active in vivo as an antidiabetic agent in the ob/ob mouse model, and has been used as an oral hypoglycemic agent in the treatment of type 2 diabetes in humans for many years.[Cayman Chemical] |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com