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ChemicalBook >> CAS DataBase List >> Hh-Ag 1.3

Hh-Ag 1.3

Hh-Ag 1.3 price.
  • $117 - $1030
  • Product name: Hh-Ag 1.3
  • CAS: 364590-63-6
  • MF: C28H28ClN3OS
  • MW: 490.06
  • EINECS:-0
  • MDL Number:MFCD14636155
  • Synonyms:3-Chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiophene-2-carboxamide;Smoothened Agonist, HCl;SAG . dihydrochloride (water soluble);Hh-Ag 1.3;3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide,hydrate,dihydrochloride;Benzo[b]thiophene-2-carboxamide, 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-;Frizzled6 agonist SAG1.3
4 prices
Selected condition：
Brand
  • Alfa Aesar
  • Sigma-Aldrich
Package
  • 1mg
  • 5mg
  • ManufacturerAlfa Aesar
  • Product numberJ64726
  • Product descriptionSmoothened Agonist dihydrochloride dihydrate
  • Packaging1mg
  • Price$117
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64726
  • Product descriptionSmoothened Agonist dihydrochloride dihydrate
  • Packaging5mg
  • Price$415
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number566660
  • Product descriptionSmoothened Agonist, SAG - CAS 364590-63-6 - Calbiochem
  • Packaging1mg
  • Price$361
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number566660
  • Product descriptionSmoothened Agonist, SAG - CAS 364590-63-6 - Calbiochem
  • Packaging5mg
  • Price$1030
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alfa Aesar J64726 Smoothened Agonist dihydrochloride dihydrate 1mg $117 2021-12-16 Buy
Alfa Aesar J64726 Smoothened Agonist dihydrochloride dihydrate 5mg $415 2021-12-16 Buy
Sigma-Aldrich 566660 Smoothened Agonist, SAG - CAS 364590-63-6 - Calbiochem 1mg $361 2024-03-01 Buy
Sigma-Aldrich 566660 Smoothened Agonist, SAG - CAS 364590-63-6 - Calbiochem 5mg $1030 2024-03-01 Buy

Properties

Boiling point :688.6±55.0 °C(Predicted)
Density :1.30±0.1 g/cm3(Predicted)
pka :10?+-.0.40(Predicted)
form :White to off-white solid.
Water Solubility :Soluble in water.
Sensitive :Light Sensitive & Hygroscopic

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Smoothened Agonist, HCl (SAG), is a highly potent activator of Smo (smoothened). This chlorobenzothiophene compound is a hedgehog pathway agonist that interacts with the heptahelical domain of Smo. SAG is shown to act as an activator at low concentrations, but can inhibit Smo coupling at very high concentrations. The activating effects of SAG will counteract Cyclopamine or Cyclopamine-KAAD inhibition of Smo.

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