Gestrinone
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- $110 - $2000
- Product name: Gestrinone
- CAS: 16320-04-0
- MF: C21H24O2
- MW: 308.41
- EINECS:685-143-2
- MDL Number:MFCD00865561
- Synonyms:(8s,13s,14s,17r)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one;13-ETHYL-17ALPHA-HYDROXY-18,19-DINORPREGNA-4,9,11-TRIEN-20-YN-3-ONE;D-GESTRINONE;GESTRINONE;9,11-trien-20-yn-3-one,13-ethyl-17-hydroxy-19-dinorpregna-(17-alpha)-1 ;ethylnorgestrienone ;gestrigone ;r-2323
10 prices
Selected condition：
Brand
- AHH
- AvaChem
- Cayman Chemical
- Chem-Impex
- DC Chemicals
Package
- 5mg
- 25mg
- 100mg
- 500mg
- 1000mg
- 1g
- 5g
- ManufacturerAHH
- Product numberMT-14194
- Product descriptionGestrinone 98%
- Packaging5g
- Price$558
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3789
- Product descriptionGestrinone
- Packaging5mg
- Price$129
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3789
- Product descriptionGestrinone
- Packaging25mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3789
- Product descriptionGestrinone
- Packaging100mg
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10006488
- Product descriptionGestrinone ≥98%
- Packaging100mg
- Price$110
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10006488
- Product descriptionGestrinone ≥98%
- Packaging500mg
- Price$459
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10006488
- Product descriptionGestrinone
- Packaging1000mg
- Price$864
- Updated2024-03-01
- Buy
- ManufacturerChem-Impex
- Product number37917
- Product descriptionGestrinone,≥98%(AssaybyTitration) ≥98%(AssaybyTitration)
- Packaging100MG
- Price$292.36
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10347
- Product descriptionGestrinone >98%
- Packaging1g
- Price$2000
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10347
- Product descriptionGestrinone >98%
- Packaging100mg
- Price$500
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-14194 | Gestrinone 98% | 5g | $558 | 2021-12-16 | Buy |
| AvaChem | 3789 | Gestrinone | 5mg | $129 | 2021-12-16 | Buy |
| AvaChem | 3789 | Gestrinone | 25mg | $290 | 2021-12-16 | Buy |
| AvaChem | 3789 | Gestrinone | 100mg | $390 | 2021-12-16 | Buy |
| Cayman Chemical | 10006488 | Gestrinone ≥98% | 100mg | $110 | 2024-03-01 | Buy |
| Cayman Chemical | 10006488 | Gestrinone ≥98% | 500mg | $459 | 2024-03-01 | Buy |
| Cayman Chemical | 10006488 | Gestrinone | 1000mg | $864 | 2024-03-01 | Buy |
| Chem-Impex | 37917 | Gestrinone,≥98%(AssaybyTitration) ≥98%(AssaybyTitration) | 100MG | $292.36 | 2021-12-16 | Buy |
| DC Chemicals | DC10347 | Gestrinone >98% | 1g | $2000 | 2021-12-16 | Buy |
| DC Chemicals | DC10347 | Gestrinone >98% | 100mg | $500 | 2021-12-16 | Buy |
Properties
Melting point :150-152°C
alpha :D20 +84.6° (c = 0.41 in methanol)
Boiling point :388.8°C (rough estimate)
Density :1.1040 (rough estimate)
refractive index :1.4900 (estimate)
storage temp. :-20°C Freezer
solubility :DMF:20.0(Max Conc. mg/mL);64.85(Max Conc. mM)
DMSO:35.0(Max Conc. mg/mL);113.48(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);64.85(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:5):0.25(Max Conc. mg/mL);81.06(Max Conc. mM)
Water:1.0(Max Conc. mg/mL);3.24(Max Conc. mM) form :A crystalline solid
pka :12.76±0.40(Predicted)
color :Off-white to light yellow
Merck :14,4415
Stability :Hygroscopic
InChI :InChI=1S/C21H24O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,9,11,13,18-19,23H,3,5-8,10,12H2,1H3/t18-,19+,20+,21+/m1/s1
InChIKey :BJJXHLWLUDYTGC-ANULTFPQSA-N
SMILES :C1C2C(CC[C@]3([H])C=2C=C[C@@]2(CC)[C@@]3([H])CC[C@]2(C#C)O)=CC(=O)C1
CAS DataBase Reference :16320-04-0(CAS DataBase Reference)
alpha :D20 +84.6° (c = 0.41 in methanol)
Boiling point :388.8°C (rough estimate)
Density :1.1040 (rough estimate)
refractive index :1.4900 (estimate)
storage temp. :-20°C Freezer
solubility :DMF:20.0(Max Conc. mg/mL);64.85(Max Conc. mM)
DMSO:35.0(Max Conc. mg/mL);113.48(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);64.85(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:5):0.25(Max Conc. mg/mL);81.06(Max Conc. mM)
Water:1.0(Max Conc. mg/mL);3.24(Max Conc. mM) form :A crystalline solid
pka :12.76±0.40(Predicted)
color :Off-white to light yellow
Merck :14,4415
Stability :Hygroscopic
InChI :InChI=1S/C21H24O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,9,11,13,18-19,23H,3,5-8,10,12H2,1H3/t18-,19+,20+,21+/m1/s1
InChIKey :BJJXHLWLUDYTGC-ANULTFPQSA-N
SMILES :C1C2C(CC[C@]3([H])C=2C=C[C@@]2(CC)[C@@]3([H])CC[C@]2(C#C)O)=CC(=O)C1
CAS DataBase Reference :16320-04-0(CAS DataBase Reference)
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Gestrinone is a synthetic steroid occasionally used to treat endometriosis. The common disease endometriosis is characterized by the presence of endometrial tissue outside the uterus which affects approximately 10% of premenopausal women. It acts centrally on the hypothalamic-pituitary system to suppress release of lutenizing hormone (LH) and follicle-stimulating hormone (FSH), thus reducing estrogen synthesis. It also binds to androgen (AR), progesterone (PR), and estrogen (ER) receptors in the human endometrial tissue but not to steroid hormone binding globulin or corticord-binding globulin. Gestrinone binds to AR and PR with EC50 values of approximately 20 and 30 nM, respectively. These values reflect approximately 5-6 fold lower affinity than testosterone and progesterone, the natural AR and PR ligands, for these receptors.More related product prices
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