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ChemicalBook >> CAS DataBase List >> Clodronate disodium

Clodronate disodium

Clodronate disodium price.
  • $13 - $2741
  • Product name: Clodronate disodium
  • CAS: 22560-50-5
  • MF: CH5Cl2NaO6P2
  • MW: 268.88
  • EINECS:245-078-9
  • MDL Number:MFCD01632786
  • Synonyms:CL2MDP;Phosphonic acid, P,P'-(dichloromethylene)bis-, sodium salt (1:2);Clodronate disodium, >=98%;DICHLOROMETHYLENEDIPHOPHONIC ACID DISODIUM SALT;DICHLOROMETHYLENEDIPHOSPHONIC ACID DISODIUM SALT;DMDP;CLODRONIC ACID DISODIUM SALT;CLODRONATE DISODIUM
23 prices
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  • Ambeed
  • American Custom Chemicals Corporation
  • Arctom
  • Biosynth Carbosynth
  • Crysdot
  • DC Chemicals
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  • ManufacturerAmbeed
  • Product numberA116381
  • Product descriptionClodronateDisodium 99%
  • Packaging100g
  • Price$2741
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA116381
  • Product descriptionClodronateDisodium 99%
  • Packaging25g
  • Price$842
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA116381
  • Product descriptionClodronateDisodium 99%
  • Packaging10g
  • Price$394
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA116381
  • Product descriptionClodronateDisodium 99%
  • Packaging5g
  • Price$242
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA116381
  • Product descriptionClodronateDisodium 99%
  • Packaging1g
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA116381
  • Product descriptionClodronateDisodium 99%
  • Packaging50mg
  • Price$22
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA116381
  • Product descriptionClodronateDisodium 99%
  • Packaging10mg
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberING0002754
  • Product descriptionCLODRONATE DISODIUM 95.00%
  • Packaging50MG
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberING0002754
  • Product descriptionCLODRONATE DISODIUM 95.00%
  • Packaging500MG
  • Price$1593.9
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS437394
  • Product descriptionClodronateDisodium 99%
  • Packaging10mg
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS437394
  • Product descriptionClodronateDisodium 99%
  • Packaging50mg
  • Price$22
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS437394
  • Product descriptionClodronateDisodium 99%
  • Packaging100mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS437394
  • Product descriptionClodronateDisodium 99%
  • Packaging1g
  • Price$79
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS437394
  • Product descriptionClodronateDisodium 99%
  • Packaging5g
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS437394
  • Product descriptionClodronateDisodium 99%
  • Packaging10g
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS437394
  • Product descriptionClodronateDisodium 99%
  • Packaging25g
  • Price$834
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A116381 ClodronateDisodium 99% 100g $2741 2021-12-16 Buy
Ambeed A116381 ClodronateDisodium 99% 25g $842 2021-12-16 Buy
Ambeed A116381 ClodronateDisodium 99% 10g $394 2021-12-16 Buy
Ambeed A116381 ClodronateDisodium 99% 5g $242 2021-12-16 Buy
Ambeed A116381 ClodronateDisodium 99% 1g $80 2021-12-16 Buy
Ambeed A116381 ClodronateDisodium 99% 50mg $22 2021-12-16 Buy
Ambeed A116381 ClodronateDisodium 99% 10mg $13 2021-12-16 Buy
American Custom Chemicals Corporation ING0002754 CLODRONATE DISODIUM 95.00% 50MG $704.55 2021-12-16 Buy
American Custom Chemicals Corporation ING0002754 CLODRONATE DISODIUM 95.00% 500MG $1593.9 2021-12-16 Buy
Arctom AS437394 ClodronateDisodium 99% 10mg $13 2021-12-16 Buy
Arctom AS437394 ClodronateDisodium 99% 50mg $22 2021-12-16 Buy
Arctom AS437394 ClodronateDisodium 99% 100mg $29 2021-12-16 Buy
Arctom AS437394 ClodronateDisodium 99% 1g $79 2021-12-16 Buy
Arctom AS437394 ClodronateDisodium 99% 5g $240 2021-12-16 Buy
Arctom AS437394 ClodronateDisodium 99% 10g $390 2021-12-16 Buy
Arctom AS437394 ClodronateDisodium 99% 25g $834 2021-12-16 Buy

Properties

Melting point :>330°C
storage temp. :room temp
solubility :Freely soluble in water, practically insoluble in ethanol (96 per cent), slightly soluble in methanol.
form :Solid
color :White to Off-White
InChIKey :HJKBJIYDJLVSAO-UHFFFAOYSA-L
CAS DataBase Reference :22560-50-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Clodronate, Disodium Salt is a first-generation bisphosphonate which are synthetic compounds characterized by a P-C-P bond. Experiments have shown that the P-C-P bond of the bisphosphonates is completely resistant to enzymatic hydrolysis. This compound has been reported to inhibit bone resorption and can be metabolized intracellularly to a β,γ-methylene analog of ATP, which in vitro is cytotoxic to macrophages. Additionally, Clodronate demonstrates the ability to cause a collapse of the mitochondrial membrane potential which eventually results in osteoclast apoptosis.

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