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ChemicalBook >> CAS DataBase List >> Cilastatin sodium

Cilastatin sodium

Cilastatin sodium price.
  • $39 - $2450
  • Product name: Cilastatin sodium
  • CAS: 81129-83-1
  • MF: C16H25N2O5S.Na
  • MW: 380.44
  • EINECS:279-694-4
  • MDL Number:MFCD08459332
  • Synonyms:Cilastatine;Cilastatin sodium;Sodium 7-(2-amino-2-carboxy-ethyl)sulfanyl-2-(2,2-dimethylcyclopropyl)carbonylamino-hept-2-enoate;Sodium hydrogen 7-[(2-amino-2-carboxylatoethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]hept-2-enoate;Sodium Cilastatin;[R-[R*,S*-(Z)]]-7-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-2-heptenoic acid monosodium salt;(Z)-7-[(R)-2-Amino-2-carboxyethylthio]-2-[(S)-2,2-dimethylcyclopropylcarbonylamino]-2-heptenoic acid 1-sodium salt;(2Z)-7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoicacidsodiumsalt
25 prices
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Brand
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • AvaChem
  • Biosynth Carbosynth
  • Chem-Impex
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
Package
  • 25mg
  • c2170000
  • 10MG
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1G
  • 2ml
  • 5g
  • 10g
  • ManufacturerAHH
  • Product numberMT-49258
  • Product descriptionCilastatin sodium 99%
  • Packaging5g
  • Price$630
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberI422
  • Product descriptionCilastatin sodium
  • Packaging50mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002011
  • Product descriptionCILASTATIN SODIUM 95.00%
  • Packaging10MG
  • Price$641.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002011
  • Product descriptionCILASTATIN SODIUM 95.00%
  • Packaging1G
  • Price$825.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002011
  • Product descriptionCILASTATIN SODIUM 95.00%
  • Packaging50MG
  • Price$952.01
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1721
  • Product descriptionCilastatin sodium salt
  • Packaging25mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1721
  • Product descriptionCilastatin sodium salt
  • Packaging100mg
  • Price$79
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1721
  • Product descriptionCilastatin sodium salt
  • Packaging250mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1721
  • Product descriptionCilastatin sodium salt
  • Packaging1g
  • Price$349
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1721
  • Product descriptionCilastatin sodium salt
  • Packaging10g
  • Price$2450
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBC164306
  • Product descriptionCilastatin sodium
  • Packaging10mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC61442
  • Product descriptionCilastatin sodium
  • Packaging25mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC61442
  • Product descriptionCilastatin sodium
  • Packaging50mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC61442
  • Product descriptionCilastatin sodium
  • Packaging100mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC61442
  • Product descriptionCilastatin sodium
  • Packaging250mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBC164306
  • Product descriptionCilastatin sodium
  • Packaging100mg
  • Price$250
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-49258 Cilastatin sodium 99% 5g $630 2021-12-16 Buy
AK Scientific I422 Cilastatin sodium 50mg $350 2021-12-16 Buy
American Custom Chemicals Corporation API0002011 CILASTATIN SODIUM 95.00% 10MG $641.55 2021-12-16 Buy
American Custom Chemicals Corporation API0002011 CILASTATIN SODIUM 95.00% 1G $825.3 2021-12-16 Buy
American Custom Chemicals Corporation API0002011 CILASTATIN SODIUM 95.00% 50MG $952.01 2021-12-16 Buy
AvaChem 1721 Cilastatin sodium salt 25mg $39 2021-12-16 Buy
AvaChem 1721 Cilastatin sodium salt 100mg $79 2021-12-16 Buy
AvaChem 1721 Cilastatin sodium salt 250mg $189 2021-12-16 Buy
AvaChem 1721 Cilastatin sodium salt 1g $349 2021-12-16 Buy
AvaChem 1721 Cilastatin sodium salt 10g $2450 2021-12-16 Buy
Biosynth Carbosynth BC164306 Cilastatin sodium 10mg $65 2021-12-16 Buy
Biosynth Carbosynth FC61442 Cilastatin sodium 25mg $75 2021-12-16 Buy
Biosynth Carbosynth FC61442 Cilastatin sodium 50mg $100 2021-12-16 Buy
Biosynth Carbosynth FC61442 Cilastatin sodium 100mg $150 2021-12-16 Buy
Biosynth Carbosynth FC61442 Cilastatin sodium 250mg $250 2021-12-16 Buy
Biosynth Carbosynth BC164306 Cilastatin sodium 100mg $250 2021-12-16 Buy

Properties

Melting point :>160°C (dec.)
Flash point :87℃
storage temp. :2-8°C
solubility :Very soluble in water and in methanol, slightly soluble in anhydrous ethanol, very slightly soluble in dimethyl sulfoxide, practically insoluble in acetone and in methylene chloride.
form :Solid
pka :pKa1 2.0; pKa2 4.4; pKa3 9.2(at 25℃)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
CAS DataBase Reference :81129-83-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Cilastatin Na (81129-83-1) is a dehydropeptidase-1 inhibitor. Inhibits the proteolytic conversion of leukotriene D4?to E4.1? Inhibits the mammalian β-lactamase renal dipeptidase (dehydropeptidase-1, DPEP1) and thus is used as an antibacterial adjunct to extend the half-life of β-lactam antibiotics.2?Cilastatin also inhibits bacterial metallo-β-lactamase and thereby may block resistance to the carbapenem family of antibiotics in certain bacteria.3? Suppresses invasion and metastasis of DPEP1-expressing tumor cells.4

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