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ChemicalBook >> CAS DataBase List >> 8-Methoxypsoralen

8-Methoxypsoralen

8-Methoxypsoralen price.
  • $7 - $7170
  • Product name: 8-Methoxypsoralen
  • CAS: 298-81-7
  • MF: C12H8O4
  • MW: 216.19
  • EINECS:206-066-9
  • MDL Number:MFCD00005009
  • Synonyms:8-Methoxy-2',3',6,7-furocoumarin;8-methoxy-2’,3’,6,7-furocoumarin ;8-Methoxy-4',5',6,7-furocoumarin;8-Methoxy-4',5':6,7-furocoumarin;8-methoxy-4’,5’,6,7-furocoumarin ;8-methoxy-4’,5’:6,7-furocoumarin ;8-Methoxy-6,7-furanocoumarin;8-Methoxyfuranocoumarin
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Brand
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Labseeker
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
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  • 25g
  • 50mg
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  • 10g
  • 10mM(in 1mL DMSO)
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-M0156-G005
  • Product description8-Methoxypsoralen ≥95%(HPLC)
  • Packaging5G
  • Price$153
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-53574
  • Product descriptionMethoxsalen 99%
  • Packaging5g
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10204
  • Product descriptionXanthotoxin
  • Packaging100mg
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA17108
  • Product description8-Methoxypsoralen, 99%
  • Packaging1g
  • Price$35.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA17108
  • Product description8-Methoxypsoralen, 99%
  • Packaging5g
  • Price$116.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA17108
  • Product description8-Methoxypsoralen, 99%
  • Packaging25g
  • Price$553.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA372661
  • Product descriptionMethoxsalen 98+%
  • Packaging10mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA372661
  • Product descriptionMethoxsalen 98+%
  • Packaging50mg
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA372661
  • Product descriptionMethoxsalen 98+%
  • Packaging1g
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA372661
  • Product descriptionMethoxsalen 98+%
  • Packaging5g
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA372661
  • Product descriptionMethoxsalen 98+%
  • Packaging10g
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA372661
  • Product descriptionMethoxsalen 98+%
  • Packaging25g
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008254
  • Product descriptionMETHOXSALEN 99.00%
  • Packaging1G
  • Price$139.65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008254
  • Product descriptionMETHOXSALEN 99.00%
  • Packaging2.5G
  • Price$796.77
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1305
  • Product description8-Methoxypsoralen
  • Packaging1g
  • Price$44
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1305
  • Product description8-Methoxypsoralen
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-M0156-G005 8-Methoxypsoralen ≥95%(HPLC) 5G $153 2021-12-16 Buy
AHH MT-53574 Methoxsalen 99% 5g $230 2021-12-16 Buy
AK Scientific J10204 Xanthotoxin 100mg $28 2021-12-16 Buy
Alfa Aesar A17108 8-Methoxypsoralen, 99% 1g $35.65 2024-03-01 Buy
Alfa Aesar A17108 8-Methoxypsoralen, 99% 5g $116.65 2024-03-01 Buy
Alfa Aesar A17108 8-Methoxypsoralen, 99% 25g $553.65 2024-03-01 Buy
Ambeed A372661 Methoxsalen 98+% 10mg $7 2021-12-16 Buy
Ambeed A372661 Methoxsalen 98+% 50mg $13 2021-12-16 Buy
Ambeed A372661 Methoxsalen 98+% 1g $21 2021-12-16 Buy
Ambeed A372661 Methoxsalen 98+% 5g $67 2021-12-16 Buy
Ambeed A372661 Methoxsalen 98+% 10g $115 2021-12-16 Buy
Ambeed A372661 Methoxsalen 98+% 25g $226 2021-12-16 Buy
American Custom Chemicals Corporation API0008254 METHOXSALEN 99.00% 1G $139.65 2021-12-16 Buy
American Custom Chemicals Corporation API0008254 METHOXSALEN 99.00% 2.5G $796.77 2021-12-16 Buy
ApexBio Technology N1305 8-Methoxypsoralen 1g $44 2021-12-16 Buy
ApexBio Technology N1305 8-Methoxypsoralen 10mM(in 1mL DMSO) $60 2021-12-16 Buy

Properties

Melting point :148-150 °C(lit.)
Boiling point :276.6°C (rough estimate)
Density :1.1344 (rough estimate)
refractive index :1.4270 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :H2O: slightly soluble
form :Needle-Like Crystals or Powder
color :white to yellow
Water Solubility :PRACTICALLY INSOLUBLE
Merck :14,5988
BRN :196453
LogP :1.523 (est)
CAS DataBase Reference :298-81-7(CAS DataBase Reference)
IARC :1 (Vol. 24, Sup 7, 100A) 2012
NIST Chemistry Reference :Methoxsalen(298-81-7)
EPA Substance Registry System :Methoxsalen (298-81-7)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

8-methoxypsoralen (also known as methoxsalen) is a naturally occurring furocoumarin compound existing in several species of plants such as Psoralea corylifolia. It is a photoactive substance that can form DNA adducts upon UVA irradiation. It is a drug used for the treatment of psoriasis, eczema, vitiligo, and some kinds of cutaneous lymphomas associated with the exposure of skin to the UVA or light from lamps or sunlight. Its mechanism of action is through inhibiting the synthesis of the deoxyribonucleic acid (DNA). After the activation, it can preferentially bind to the guanine and cytosine molecules of DNA, further leading to the cross-linking of DNA, thus inhibiting the DNA synthesis. It can further inhibit the RNA and protein synthesis at high concentration. It is extracted from Ammi majus.

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