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ChemicalBook >> CAS DataBase List >> 4-AMINO-1-TERT-BUTYL-3-(1'-NAPHTHYL)PYRAZOLO[3,4-D]PYRIMIDINE

4-AMINO-1-TERT-BUTYL-3-(1'-NAPHTHYL)PYRAZOLO[3,4-D]PYRIMIDINE

4-AMINO-1-TERT-BUTYL-3-(1'-NAPHTHYL)PYRAZOLO[3,4-D]PYRIMIDINE price.
  • $23 - $1600
  • Product name: 4-AMINO-1-TERT-BUTYL-3-(1'-NAPHTHYL)PYRAZOLO[3,4-D]PYRIMIDINE
  • CAS: 221243-82-9
  • MF: C19H19N5
  • MW: 317.39
  • EINECS:
  • MDL Number:MFCD03425471
  • Synonyms:4-AMINO-1-TERT-BUTYL-3-(1'-NAPHTHYL)PYRAZOLO[3,4-D]PYRIMIDINE;1-NA-PP1;1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine;1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;1-Naphthyl PP1;1-NAPHTHYL PP1(1-NA-PP 1);CS-2001;1H-Pyrazolo[3,4-d]pyrimidin-4-amine,1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-
33 prices
Selected condition:
Brand
  • Alichem
  • Ambeed
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • SynChem
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAlichem
  • Product number221243829
  • Product description1-NaphthylPP1
  • Packaging50mg
  • Price$453.99
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number221243829
  • Product description1-NaphthylPP1
  • Packaging100mg
  • Price$686.07
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA252944
  • Product description1-(tert-Butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 98+%
  • Packaging5mg
  • Price$89
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA252944
  • Product description1-(tert-Butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 98+%
  • Packaging10mg
  • Price$155
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA252944
  • Product description1-(tert-Butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 98+%
  • Packaging25mg
  • Price$272
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8605
  • Product description1-NaphthylPP1
  • Packaging5mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8605
  • Product description1-NaphthylPP1
  • Packaging10mg
  • Price$229
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8605
  • Product description1-NaphthylPP1
  • Packaging50mg
  • Price$920
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8605
  • Product description1-NaphthylPP1
  • Packaging100mg
  • Price$1559
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA10426
  • Product description4-Amino-1-tert-butyl-3-(1'-naphthyl)pyrazolo[3,4-d]pyrimidine
  • Packaging5mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA10426
  • Product description4-Amino-1-tert-butyl-3-(1'-naphthyl)pyrazolo[3,4-d]pyrimidine
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA10426
  • Product description4-Amino-1-tert-butyl-3-(1'-naphthyl)pyrazolo[3,4-d]pyrimidine
  • Packaging25mg
  • Price$187.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10954
  • Product description1-NA-PP1 ≥98%
  • Packaging1mg
  • Price$23
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10954
  • Product description1-NA-PP1 ≥98%
  • Packaging5mg
  • Price$104
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10954
  • Product description1-NA-PP1 ≥98%
  • Packaging10mg
  • Price$180
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10954
  • Product description1-NA-PP1 ≥98%
  • Packaging50mg
  • Price$717
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alichem 221243829 1-NaphthylPP1 50mg $453.99 2021-12-16 Buy
Alichem 221243829 1-NaphthylPP1 100mg $686.07 2021-12-16 Buy
Ambeed A252944 1-(tert-Butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 98+% 5mg $89 2021-12-16 Buy
Ambeed A252944 1-(tert-Butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 98+% 10mg $155 2021-12-16 Buy
Ambeed A252944 1-(tert-Butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 98+% 25mg $272 2021-12-16 Buy
ApexBio Technology A8605 1-NaphthylPP1 5mg $130 2021-12-16 Buy
ApexBio Technology A8605 1-NaphthylPP1 10mg $229 2021-12-16 Buy
ApexBio Technology A8605 1-NaphthylPP1 50mg $920 2021-12-16 Buy
ApexBio Technology A8605 1-NaphthylPP1 100mg $1559 2021-12-16 Buy
Biosynth Carbosynth FA10426 4-Amino-1-tert-butyl-3-(1'-naphthyl)pyrazolo[3,4-d]pyrimidine 5mg $55 2021-12-16 Buy
Biosynth Carbosynth FA10426 4-Amino-1-tert-butyl-3-(1'-naphthyl)pyrazolo[3,4-d]pyrimidine 10mg $85 2021-12-16 Buy
Biosynth Carbosynth FA10426 4-Amino-1-tert-butyl-3-(1'-naphthyl)pyrazolo[3,4-d]pyrimidine 25mg $187.5 2021-12-16 Buy
Cayman Chemical 10954 1-NA-PP1 ≥98% 1mg $23 2024-03-01 Buy
Cayman Chemical 10954 1-NA-PP1 ≥98% 5mg $104 2024-03-01 Buy
Cayman Chemical 10954 1-NA-PP1 ≥98% 10mg $180 2024-03-01 Buy
Cayman Chemical 10954 1-NA-PP1 ≥98% 50mg $717 2024-03-01 Buy

Properties

Melting point :219-222°C
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become ‘a(chǎn)nalog sensitive’ (as), as compared to the wild-type kinase. 1-NA-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 1.5 nM versus 1.0 μM, respectively). The homologous mutation in other kinases generated similar analog sensitivity (e.g., IC50 = 1.5 nM for c-Fyn-as1 versus 0.6 μM for c-Fyn; 7.0 nM for c-Abl-as2 versus 0.6 μM for c-Abl; 15 nM for Cdk2-as1 versus 18 μM for Cdk2). This approach has been used to elucidate functions of several kinases in both mammalian and yeast systems.

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