2-Acetylphenothiazine
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- $21 - $2632.89
- Product name: 2-Acetylphenothiazine
- CAS: 6631-94-3
- MF: C14H11NOS
- MW: 241.31
- EINECS:229-626-4
- MDL Number:MFCD00005017
- Synonyms:2-ACETYLPHENOTHIAZINE;methyl phenothiazin-2-yl ketone;2-Acetyl-10H-phenothiazine;2-Acetylphenothiazin;1-(10H-Phenothiazin-2-yl)ethan-1- one, 2-Ethanoyl-10H-phenothiazine;ML 171;LABOTEST-BB LT00012652;NOX1 Inhibitor, ML171
35 prices
Selected condition：
Brand
- AHH
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- Medical Isotopes, Inc.
- Sigma-Aldrich
- SynQuest Laboratories
- TCI Chemical
- TRC
- Usbiological
Package
- 10mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1g
- 5G
- 10g
- 25g
- 50g
- 100g
- 500g
- 10mM(in 1mL DMSO)
- ManufacturerAHH
- Product numberMT-32712
- Product description2-Acetylphenothiazine 95%
- Packaging500g
- Price$460
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberL150
- Product description2-Acetylphenothiazine
- Packaging1g
- Price$21
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberL150
- Product description2-Acetylphenothiazine
- Packaging25g
- Price$145
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberL150
- Product description2-Acetylphenothiazine
- Packaging100g
- Price$241
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0020110
- Product description2-ACETYLPHENOTHIAZINE 95.00%
- Packaging25G
- Price$1156.6
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0020110
- Product description2-ACETYLPHENOTHIAZINE 95.00%
- Packaging100G
- Price$2632.89
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5672
- Product descriptionML171
- Packaging50mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5672
- Product descriptionML171
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA01622
- Product description2-Acetylphenothiazine
- Packaging50mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA01622
- Product description2-Acetylphenothiazine
- Packaging100mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA01622
- Product description2-Acetylphenothiazine
- Packaging250mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA01622
- Product description2-Acetylphenothiazine
- Packaging500mg
- Price$375
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA01622
- Product description2-Acetylphenothiazine
- Packaging1g
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19056
- Product description2-Acetylphenothiazine ≥98%
- Packaging10g
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19056
- Product description2-Acetylphenothiazine ≥98%
- Packaging25g
- Price$70
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19056
- Product description2-Acetylphenothiazine ≥98%
- Packaging50g
- Price$131
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-32712 | 2-Acetylphenothiazine 95% | 500g | $460 | 2021-12-16 | Buy |
| AK Scientific | L150 | 2-Acetylphenothiazine | 1g | $21 | 2021-12-16 | Buy |
| AK Scientific | L150 | 2-Acetylphenothiazine | 25g | $145 | 2021-12-16 | Buy |
| AK Scientific | L150 | 2-Acetylphenothiazine | 100g | $241 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0020110 | 2-ACETYLPHENOTHIAZINE 95.00% | 25G | $1156.6 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0020110 | 2-ACETYLPHENOTHIAZINE 95.00% | 100G | $2632.89 | 2021-12-16 | Buy |
| ApexBio Technology | B5672 | ML171 | 50mg | $40 | 2021-12-16 | Buy |
| ApexBio Technology | B5672 | ML171 | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA01622 | 2-Acetylphenothiazine | 50mg | $85 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA01622 | 2-Acetylphenothiazine | 100mg | $150 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA01622 | 2-Acetylphenothiazine | 250mg | $225 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA01622 | 2-Acetylphenothiazine | 500mg | $375 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA01622 | 2-Acetylphenothiazine | 1g | $600 | 2021-12-16 | Buy |
| Cayman Chemical | 19056 | 2-Acetylphenothiazine ≥98% | 10g | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 19056 | 2-Acetylphenothiazine ≥98% | 25g | $70 | 2024-03-01 | Buy |
| Cayman Chemical | 19056 | 2-Acetylphenothiazine ≥98% | 50g | $131 | 2024-03-01 | Buy |
Properties
Melting point :180-185 °C (lit.)
Boiling point :455.7±34.0 °C(Predicted)
Density :1.249±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
pka :-2.45±0.20(Predicted)
form :Dark yellow-orange powder
color :Yellow to Dark Orange
λmax :244nm(MeOH)(lit.)
CAS DataBase Reference :6631-94-3(CAS DataBase Reference)
Boiling point :455.7±34.0 °C(Predicted)
Density :1.249±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
pka :-2.45±0.20(Predicted)
form :Dark yellow-orange powder
color :Yellow to Dark Orange
λmax :244nm(MeOH)(lit.)
CAS DataBase Reference :6631-94-3(CAS DataBase Reference)
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
2-Acetylphenothiazine (2-APT) is a selective, cell-active inhibitor of NADPH oxidase 1 (NOX1) that blocks the generation of reactive oxygen species (ROS) in HT-29 cells with an IC50 value of 0.129 μM. It does not affect xanthine oxidase-dependent or mitochondrial ROS generation. 2-APT prevents ROS-dependent formation of ECM-degrading invadopodia in colon cancer cells. It also abolishes collagen-induced superoxide production by platelets (IC50 = 306 nM), preventing platelet aggregation and thrombus formation. 2-APT protects beta cells from cytokine-induced apoptosis by inhibiting NOX1. 2-APT can also activate the human transient receptor potential ankyrin 1 (TRPA1) nociceptor at 1-30 μM.Related product price
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