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ACS Omega

ACS Omega

IF: 3.7
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Daidzein from Dietary Supplement to a Drug Candidate: An Evaluation of Potential

Published:27 August 2023 DOI: 10.1021/acsomega.3c03741
Mohammed Ubaid,  Salauddin, Md Andalib Shadani, S. M. Kawish, Mohammed Albratty, Hafiz A. Makeen, Hassan A. Alhazmi, Asim Najmi, Khalid Zoghebi, Maryam A. Halawi, Abuzer Ali, Md Shamsher Alam*, Zeenat Iqbal* and Mohd. Aamir Mirza*, 

Abstract

Daidzein (DDZ) is a well-known nutraceutical supplement belonging to the class of isoflavones. It is isolated from various sources such as alfalfa, soybean, and red clover. It demonstrates a broad array of pharmacological/beneficial properties such as cardiovascular exercise, cholesterol reduction, and anticancer, antifibrotic, and antidiabetic effects, which make it effective in treating a wide range of diseases. Its structure and operation are the same as those of human estrogens, which are important in preventing osteoporosis, cancer, and postmenopausal diseases. It is thus a promising candidate for development as a phytopharmaceutical. Addressing safety, efficacy, and physicochemical properties are the primary prerequisites. DDZ is already ingested every day in varying amounts, so there should not be a significant safety risk; however, each indication requires a different dose to be determined. Some clinical trials are already being conducted globally to confirm its safety, efficacy, and therapeutic potential. Furthermore, as a result of its therapeutic influence on health, in order to establish intellectual property, patents are utilized. In light of the vast potential of eugenol, this review presents a detailed data collection on DDZ to substantiate the claim to develop it in the therapeutic category.

Substances (3)

Related products
Procduct Name CAS Molecular Formula Supplier Price
Eugenol 97-53-0 C10H12O2 803 suppliers $5.00-$2271.36
Daidzein 486-66-8 C15H10O4 646 suppliers $5.00-$12190.00
DDZ (2,2-DIMETHYL-3,5-DIMETHYOXY-BENZYLOXY-BENZOCARBONATE) 1 suppliers Inquiry

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