成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

ChemicalBook >> journal list >> Infection and Chemotherapy >>article

Infection and Chemotherapy

IF: 2.79
Download PDF

Praziquantel treatment in trematode and cestode infections: an update.

Published:1 March 2013 DOI: 10.3947/ic.2013.45.1.32 PMID: 24265948
Jong-Yil Chai

Abstract

Status and emerging issues in the use of praziquantel for treatment of human trematode and cestode infections are briefly reviewed. Since praziquantel was first introduced as a broadspectrum anthelmintic in 1975, innumerable articles describing its successful use in the treatment of the majority of human-infecting trematodes and cestodes have been published. The target trematode and cestode diseases include schistosomiasis, clonorchiasis and opisthorchiasis, paragonimiasis, heterophyidiasis, echinostomiasis, fasciolopsiasis, neodiplostomiasis, gymnophalloidiasis, taeniases, diphyllobothriasis, hymenolepiasis, and cysticercosis. However, Fasciola hepatica and Fasciola gigantica infections are refractory to praziquantel, for which triclabendazole, an alternative drug, is necessary. In addition, larval cestode infections, particularly hydatid disease and sparganosis, are not successfully treated by praziquantel. The precise mechanism of action of praziquantel is still poorly understood. There are also emerging problems with praziquantel treatment, which include the appearance of drug resistance in the treatment of Schistosoma mansoni and possibly Schistosoma japonicum, along with allergic or hypersensitivity reactions against praziquantel treatment. To cope with and overcome these problems, combined use of drugs, i.e., praziquantel and other newly introduced compounds such as triclabendazole, artemisinins, and tribendimidine, is being tried.

Substances (4)

Related products
Procduct Name CAS Molecular Formula Supplier Price
Artemisinin 63968-64-9 C15H22O5 722 suppliers $5.00-$2700.00
Praziquantel 55268-74-1 C19H24N2O2 698 suppliers $5.00-$1504.50
Triclabendazole 68786-66-3 C14H9Cl3N2OS 409 suppliers $5.00-$590.00
tribendimidine 115103-15-6 C28H32N6 49 suppliers Inquiry

Similar articles

IF:3.2

Dutasteride in Androgenetic Alopecia: An Update.

Current clinical pharmacology Tasleem Arif, Konchok Dorjay,etc Published: 1 January 2017
IF:2.1

Depot-medroxyprogesterone acetate: an update

Archives of Gynecology and Obstetrics Sayed Bakry, Zaher O. Merhi,etc Published: 10 May 2008
IF:2.8

Role of isavuconazole in the treatment of invasive fungal infections.

Therapeutics and Clinical Risk Management Dustin T Wilson, V Paul Dimondi,etc Published: 3 August 2016