價格 | ¥198 | ¥448 | ¥648 |
包裝 | 1mg | 5mg | 10mg |
最小起訂量 | 1mg |
發(fā)貨地 | 上海 |
更新日期 | 2024-12-02 |
中文名稱:木二糖 | 英文名稱:XYLOBIOSE |
CAS:6860-47-5 | 品牌: TargetMol |
產(chǎn)地: 美國 | 保存條件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
純度規(guī)格: 99.84% | 產(chǎn)品類別: 抑制劑 |
貨號: T5788 |
名稱 | XYLOBIOSE |
描述 | XYLOBIOSE ia a natural product,and exhibited therapeutic potential for treating obesity which involved suppression of fat deposition and obesity-related metabolic disorders. |
動物實驗 | The mice were randomized into five groups: (a) a control group (Ctrl, n = 10) which received a diet of modified American Institute of Nutrition (AIN)-93G (17% of the calories are from fat); (b) a high fat diet (HFD)-induced obesity control group (HF, n = 13) which received a HFD comprised of 60% fat; (c) a xylose 15% group (Xylo 15) which received a HFD with 15% of the total sucrose replaced with d-xylose (n = 13); (d) an XYLOBIOSE 10% group (XYLOBIOSE 10, n = 13) which received a HFD with 10% of the total sucrose replaced by XYLOBIOSE; and (e) an XYLOBIOSE 15% group (XYLOBIOSE 15, n = 12) which received a HFD with 15% of the total sucrose replaced by XYLOBIOSE. Commercially available D-xylose was included as a positive control and was administered at a dose comparable to XYLOBIOSE. The mice were maintained on these diets according to their group for ten weeks prior to sacrifice. Body weight and food intake were measured twice a week. |
體內(nèi)活性 | 小鼠接受含60%高脂飲食,其中包含15%的d-xylose、10%或15%的XYLOBIOSE,作為總蔗糖含量的一部分,持續(xù)十周。XYLOBIOSE補(bǔ)充顯著降低了體重、脂肪和肝臟重量、空腹血糖以及血脂水平。同時,XYLOBIOSE補(bǔ)充還改善了瘦素和脂肪細(xì)胞因子水平,并且在網(wǎng)膜脂肪和肝臟中調(diào)低了脂肪生成和脂肪細(xì)胞生成基因的表達(dá)。此外,XYLOBIOSE補(bǔ)充還降低了網(wǎng)膜脂肪中的促炎細(xì)胞因子、脂肪酸攝取、脂解作用和β-氧化相關(guān)基因的表達(dá)水平[1]。XYLOBIOSE通過調(diào)節(jié)miR-122a/33a軸,在db/db小鼠中展示了抗糖尿病、降脂和抗炎的效果[2]。 |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 60 mg/mL (212.58 mM) |
關(guān)鍵字 | inhibit | Inhibitor | Disaccharide | XYLOBIOSE |
相關(guān)產(chǎn)品 | Lenalidomide | Fisetin | Apremilast | Amlexanox | Bornyl acetate | Diallyl disulfide | Glucosamine | Inosine pranobex | Dexamethasone acetate | Dexamethasone | Acetylcysteine | L-Arginine |
相關(guān)庫 | 微生物天然產(chǎn)物庫 | 經(jīng)典已知活性庫 | 已知活性化合物庫 | 抗癌天然產(chǎn)物庫 | 抗衰老化合物庫 | 化妝品成分化合物庫 | 天然產(chǎn)物庫 | 高通量篩選天然產(chǎn)物庫 |
成立日期 | 2013-04-18 (12年) | 注冊資本 | 566.2651萬人民幣 |
員工人數(shù) | 100-500人 | 年營業(yè)額 | ¥ 1億以上 |
主營行業(yè) | 化學(xué)試劑,生物活性小分子 | 經(jīng)營模式 | 貿(mào)易,試劑,定制,服務(wù) |
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