中文名：黃芩素

英文名：Baicalein

中文別名：三羥黃酮

英文別名：SpecPlus_000758|Spectrum5_001418|W-202870|baicalein|BAICALEIN [WHO-DD]|MFCD00017459|SDCCGMLS-0066744.P001|NCGC00025282-01|NCGC00025282-02|NCGC00025282-03|BAICALEIN [INCI]|Baicalein, 98%|HMS3412F14|HMS3655P18|MLS002473007|NCGC00017236-03|NSC661431|NSC-6614

純度：分析標準品,≥98%

貨號：B107323

包裝：20mg

Cas號：491-67-8

存儲溫度：2-8°C儲存

產(chǎn)品介紹：

Baicalein is a cell-permeable flavone, originally isolated from the roots of Scutellaria baicalensis, that inhibits cellular Ca2+ uptake, calcium mobilization, and adjuvant-induced arthritis. Baicalein has been shown to inhibit platelet 5-LO (5-lipoxygenase) (IC50=9.5 mM) and 12-LO (12-lipoxygenases) (IC50=0.12 mM) and reverse transcriptase. Baicalein reduces leukotriene biosynthesis and inhibits the release of lysosomal enzymes. Baicalein is a potent anti-inflammatory and anti-tumor agent, and it blocks PREP (prolyl oligopeptidase). Baicalein induces the S-phase arrest and apoptosis in proliferation of human lung squamous carcinoma CH27 cells. The declining expression of cdk1, cdk2, cyclin D2 and cyclin A by Baicalein resulted in the G1 and G2 cell cycle arrest in C6 rat glioma cells. Baicalein has anti-thrombotic, antiproliferative and anti-mitogenic effects. Baicalein inhibits protein tyrosine kinase in leukemia (CEM) cells and PMA-stimulated PKC (protein kinase C). Baicalein is an inhibitor of 15-LO and CYP2C9.An inhibitor of Ca2+ uptake, 5-LO, and 12-LO

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