Host:Rabbit
Target Protein:Nephrin
IR:Immunogen Range:451-550/1241
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4868
Swiss Prot:O60500
Source:KLH conjugated synthetic peptide derived from human Nephrin:451-550/1241
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
Flow-Cyt(1μg/Test)
Cross Reactive Species:Human
Mouse
Rat
Dog
Rabbit
本產品僅供科研使用。不能用于人和動物治療等其它臨床診斷使用！
關鍵字： CNF;NPHN;NPHS1;NPHS 1;Nephrin;
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