Anti-TSLP antibody (humanized ,1A1A）
Anti-TSLP抗體
PRODUCT DETAILS
Product Name Anti-TSLP antibody
Species Reactivity Human, Primate
Source Recombinant chimeric antibody (mouse)
Isotype IgG1-kappa (human)
Expression System HEK 293 cell
Purification Protein A purified
Label Unconjugated
Formulation Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose
Reconstitution Centrifuge vial prior to opening vial. Add 0.5 mL sterile water or 0.01M PBS (pH7.2) at 0.4 mg/mL. Gently pipet solution down the sides of the vial.
DO NOT VORTEX.
Please note: For research use only. Not for diagnostic or therapeutic use.
SHIPPING & STROAGE
Shipping Lyophilized product is shipped at ambient temperature.
Storage Upon receipt, store immediately at -20 to -70°C:12 months from date of receipt. After reconstitution under sterile conditions: 2 to 8 °C or 1 month or -20 to -70°C for 6 months.
Avoid freeze-thaw cycles.
APPLICATIONS
Item Description Data Examples
Immunoassay Ligand Binding-Sandwich ELISA
In a sandwich ELISA, a concentration of 1 μg/mL (100 μL/well) of recombinant human TSLP (Cat.#: 0721061) will be detected by the Anti-TSLP Ab (Cat.#: 0731062) when used with goat anti-human IgG(H+L) as the secondary antibody. The EC50 is 92 ng/mL.
Neutralization Inhibiting STAT-5 Signaling
The stimulation of STAT5-Luciferase expression by the recombinant human TSLP (Cat.#: 0721061) in the HEK293 cells (Cat.#: 0611142) is neutralized by the Anti-TSLP antibody (Cat.#: 0731062) in a dose-dependent manner. The ND50 is typically 6.21 μg/mL.
Blocking TSLPR binding
In a sandwich ELISA, a concentration of 1μg/mL (100 μL/well) of anti-TSLP Ab (Cat.#: 0731062) will block binding of recombinant human TSLPR (1 μg/mL) (Cat. #: 0721112) to the recombinant human TSLP (Cat.#: 0721061) in a dose-dependent manner. The ND50 is 1.49 μg/mL.
Please note: Optimal concentrations should be determined by each application for each lab.
匯智泰康是一家位于中美兩地的生物醫(yī)藥合同研發(fā)機構(gòu)，整合中美兩地的藥物研發(fā)技術(shù)服務(wù)平臺，基于AAALAC、GLP、ISO/IEC 17025實驗室認證，面向全球企業(yè)及研發(fā)機構(gòu)提供分析化學(xué)、DMPK、藥理藥效、生物學(xué)、以及毒理安全性評價產(chǎn)品與服務(wù)。
主要產(chǎn)品：
體外藥物代謝產(chǎn)品
Ⅰ相代謝穩(wěn)定性試劑盒
Ⅱ相代謝穩(wěn)定性試劑盒
CYP450酶代謝表型研究試劑盒
NADPH再生系統(tǒng)，UGT孵育系統(tǒng)
不同種屬肝微粒體，肝S9
細胞色素P450酶，代謝底物，代謝產(chǎn)物，抑制劑等
遺傳毒性產(chǎn)品
遺傳毒性Ames試劑盒
體外染色體畸變試驗試劑盒
TK基因突變試驗試劑盒
HPGRT基因突變試劑盒
彗星試驗試劑盒
誘導(dǎo)大鼠肝S9等
空白生物基質(zhì)
空白血清：食蟹猴，恒河猴，比格犬，大鼠，小鼠等
空白血漿：食蟹猴，恒河猴，比格犬，大鼠，小鼠等
空白全血：食蟹猴，恒河猴，比格犬，大鼠，小鼠等
空白尿液：食蟹猴，恒河猴，比格犬，大鼠，小鼠等
空白膽汁：食蟹猴，恒河猴，比格犬，大鼠，小鼠等
關(guān)鍵字： TSLPAntybody;TSLP抗體;抗體;
匯智泰康是一家位于中美兩地的生物醫(yī)藥合同研發(fā)機構(gòu)，整合中美兩地的藥物研發(fā)技術(shù)服務(wù)平臺，基于AAALAC、GLP、ISO/IEC 17025實驗室認證，面向全球企業(yè)及研發(fā)機構(gòu)提供分析化學(xué)、DMPK、藥理藥效、生物學(xué)、以及毒理安全性評價產(chǎn)品與服務(wù)。