PD 198306 NEW
| Price | $58 | $141 | $198 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-14 |
Product Details
| Product Name: PD 198306 | CAS No.: 212631-61-3 |
| Purity: 99.75% | Supply Ability: 10g |
| Release date: 2024/11/14 |
Product Introduction
Bioactivity
| 名稱 | PD 198306 |
| 描述 | PD 198306 is a selective inhibitor of MAPK/ERK-kinase (MEK) with antihyperalgesic effects. PD 198306 reduces the Streptozocin-induced increase in the level of active ERK1. |
| 體外活性 | PD 198306 (10?μM) reduces Tha-Crimson replication by 30% at 18?h and 50% at 36?h. PD 198306 (10? μM) significantly inhibits Tha-GFP replication by 25%[1]. |
| 體內(nèi)活性 | In male Sprague Dawley rats bearing neuropathic pain, PD 198306 (1-30 μg/10 μL; i.t.) dose-dependently blocks static allodynia in both the chronic constriction injury and the streptozocin models[2]. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 45 mg/mL (94.49 mM) |
| 關(guān)鍵字 | MAPK | inhibit | neuropathic | Inhibitor | MAP2K | rabies | mitogen-activated protein | drug | MAPKK | phosphatases | inositol | RNA | pain | PD198306 | interference | MEK | ERK | PD 198306 | antihyperalgesic | screening | Mitogen-activated protein kinase kinase | phosphate | kinases | PD-198306 |
| 相關(guān)產(chǎn)品 | Lidocaine | Refametinib R enantiomer | Binimetinib | Lidocaine hydrochloride | Selumetinib | U0126-EtOH | Refametinib | Honokiol | Pelitinib | Trametinib | PD184161 | PD98059 |
| 相關(guān)庫(kù) | 抗結(jié)直腸癌化合物庫(kù) | 經(jīng)典已知活性庫(kù) | 疼痛相關(guān)化合物庫(kù) | 激酶抑制劑庫(kù) | 抗肥胖化合物庫(kù) | 抑制劑庫(kù) | 抗前列腺癌化合物庫(kù) | 已知活性化合物庫(kù) | 抗癌化合物庫(kù) | 抗肝癌化合物庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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