PD 151746 NEW
| Price | $59 | $98 | $198 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-06 |
Product Details
| Product Name: PD 151746 | CAS No.: 179461-52-0 |
| Purity: ≥98% | Supply Ability: 10g |
| Release date: 2024/11/06 |
Product Introduction
Bioactivity
| 名稱 | PD 151746 |
| 描述 | PD151746 is a calpain inhibitor with a 20-fold selectivity for u-calpain (Ki = 0.26 ± 0.03 μM) over m-calpain (Ki = 5.33 ± 0.77 μM). Its IC50 values are 0.26 ± 0.03 μM (Ki for μ-calpain) and 5.33 ± 0.77 μM (Ki for m-calpain) [1]. In vitro, PD151746 targets calpain and reduces oxLDL-induced cytotoxicity [2]. |
| 體內(nèi)活性 | PD151746 reduces the cytotoxicity induced by oxidized low-density lipoprotein (oxLDL) in HMEC-1 cells. It also effectively mitigates the hydrolysis of SLLVY-AMC induced by marine toxins in SY5Y cells. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 44 mg/mL (185.5 mM) Ethanol : 44 mg/mL (185.5 mM) H2O : < 1 mg/mL (insoluble or slightly soluble) |
| 關(guān)鍵字 | PD-151746 | PD151746 | PD 151746 |
| 相關(guān)產(chǎn)品 | Papain | 2-Aminoethanethiol | (S)-(+)-Ibuprofen | PMSF | Sitagliptin | N-Ethylmaleimide | Sitagliptin phosphate monohydrate | Aloxistatin | Linagliptin | Vildagliptin | Alloxan monohydrate | 4'-Hydroxychalcone |
| 相關(guān)庫(kù) | 經(jīng)典已知活性庫(kù) | 泛素化化合物庫(kù) | HIF-1化合物庫(kù) | 蛋白酶抑制劑庫(kù) | 抑制劑庫(kù) | NO PAINS 化合物庫(kù) | 已知活性化合物庫(kù) | 共價(jià)抑制劑庫(kù) | 含氟化合物庫(kù) | 抗代謝疾病化合物庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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