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Postion:Product Catalog >PD 169316
PD 169316
  • PD 169316
  • PD 169316

PD 169316

Price Get Latest Price
Package 1g 5g 10g
Min. Order: 1g
Supply Ability: 1000
Update Time: 2025-01-10

Product Details

Product Name: PD 169316 CAS No.: 152121-53-4
Min. Order: 1g Purity: 98
Supply Ability: 1000 Release date: 2025/01/10

Product Name:    PD 169316

Synonyms:    PD 169316, >97%;CS-497;PD 169316 - CAS 152121-53-4 - Calbiochem;4-[5-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-iMidazol-4-yl]pyridine;Pyridine, 4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-iMidazol-5-yl]-;PD169316/PD-169316;4-[4-(4-Fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine;4-[4-(4-Fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine PD 169316

CAS:    152121-53-4

MF:    C20H13FN4O2

MW:    360.34

EINECS:    200-256-5

Product Categories:    Inhibitors;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators

p38 is a member of the mitogen-activated protein kinase (MAPK) superfamily of enzymes that play an important role in signal transduction. PD 169316 is a selective inhibitor of p38 MAPK. It inhibits p38 MAPK with an IC50 of 89 nM, whereas the IC50s are >100-fold higher for extracellular signal-regulated kinase (ERK) and >1,000-fold higher for protein kinase A (PKA) and PKCα. PD 169316 inhibits apoptosis of neuronal and non-neuronal cells deprived of specific trophic factors such as potassium or nerve growth factor.


Company Profile Introduction

Wuhan Circle Star Chem-medical Technology Co.,Ltd is located in wuhan, the central city of China, the core of the Changjiang river economic belt and known as the "thoroughfare of nine provinces".Mainly engaged in electronic chemicals, pharmaceutical intermediates, pesticide intermediates, ultraviolet absorbent, food additives and other fine chemical products research and development, production, sales and operation or agency of various products and technology import and export business. The company has two laboratories (located in wuhan and ningbo), a Chinese workshop (located in wuhan), and two amplification production bases (located in zhejiang and hubei).The company employs a number of postdocs, doctors and professors from wuhan university, huazhong agricultural university, huazhong university of science and technology and other famous universities in China to form the r&d team, and also has its own excellent sales team. The company always adhere to the "technology first, customer first, quality after-sales service" professional philosophy and enterprise spirit.The company can provide excellent products, technical support and perfect after-sales service, and ensure the quality and timely delivery regardless of business size.In order to establish a good reputation among domestic and foreign customers.

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