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S-腺苷甲硫氨酸對甲苯磺酸鹽

S-腺苷甲硫氨酸對甲苯磺酸鹽

中文名稱S-腺苷甲硫氨酸對甲苯磺酸鹽
中文同義詞S-腺甙甲硫氨酸對甲苯磺酸鹽;S-腺苷甲硫氨酸對甲苯磺酸鹽;S-腺苷甲硫氨酸對甲苯磺酸鹽(S-腺甙甲硫氨酸對甲苯磺酸鹽);S-腺苷甲硫氨酸對甲苯磺酸鹽 17176-17-9/;腺苷蛋氨酸甲苯磺酸鹽;S-腺苷-L-蛋氨酸甲磺酸鹽;S-腺苷-L-甲硫氨酸(苯磺酸鹽)
英文名稱S-Adenosyl-L-methionine tosylate
英文同義詞S-ADENOSYLMETHIONINE TOSYLATE;S-Adenosyl-L-methionine tosylate;S-(5'-ADENOSYL)-L-METHIONINE P-TOLUENESULFONATE;S-(5'-ADENOSYL)-L-METHIONINE TOLUENE-4-SULFONATE;SAM-E;S-(5'-ADENOSYL)-L-METHIONINETOLUENE- &;S-ADENOSYL-L-METHIONINE (SAME);S-(5''-Adenosyl)-L-methionine-4-toluenesulfonate
CAS號71914-80-2
分子式C15H23N6O5S.C7H7O3S
分子量570.64
EINECS號
相關(guān)類別醫(yī)藥原料;化學(xué)試劑;醫(yī)用原料
Mol文件71914-80-2.mol
結(jié)構(gòu)式S-腺苷甲硫氨酸對甲苯磺酸鹽 結(jié)構(gòu)式

S-腺苷甲硫氨酸對甲苯磺酸鹽 性質(zhì)

儲存條件−20°C
溶解度H2O:0.1 g/mL,澄清

S-腺苷甲硫氨酸對甲苯磺酸鹽 用途與合成方法

S-Adenosyl-L-methionine tosylate (S-Adenosyl methionine tosylate) 是通過蛋氨酸腺苷轉(zhuǎn)移酶的作用由蛋氨酸和 ATP 內(nèi)源性生產(chǎn)的,是一種重要的具有口服活性的甲基供體。S-Adenosyl-L-methionine tosylate 是一種具有有效的抗抑郁和鎮(zhèn)痛作用的膳食補充劑,并可用于肝病和骨關(guān)節(jié)炎的研究。

S-Adenosyl-L-methionine (Ademetionine) is involved in three main metabolic pathways: 1) methylation, as the principal source of methyl groups in the body; 2) transsulfuration, S-Adenosyl-L-methionine forms S-Adenosylhomocysteine (SAH) and then converted to homocysteine (Hcy) which can be converted to cystathionine then to cysteine and the sulfate (SO4) donated to other metabolic intermediates; and 3) aminopropylation, as S-Adenosyl-L-methionine plays an important role in the synthesis of polyamines which can eventually form and recycle methionine.
In vitro studies using human articular chondrocytes have shown S-Adenosyl-L-methionine-induced increases in proteoglycan synthesis and proliferation rates in rabbits.

Mice lacking methionine adenosyltransferase 1a (Mat1a) have reduced hepatic S-Adenosyl-L-methionine levels and develop oxidative stress, steatohepatitis, and hepatocellular carcinoma (HCC). However, injury and HCC also occur if hepatic S-Adenosyl-L-methionine level is excessive chronically. Thus a normal hepatic S-Adenosyl-L-methionine level is necessary to maintain liver health and prevent injury and HCC.

安全信息

WGK Germany3
F1-10

MSDS信息

提供商 語言
英文
更新日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價格
2024/11/08HY-B0617AS-腺苷甲硫氨酸對甲苯磺酸鹽
S-Adenosyl-L-methionine tosylate
71914-80-250mg750元
2024/11/08HY-B0617AS-腺苷甲硫氨酸對甲苯磺酸鹽
S-Adenosyl-L-methionine tosylate
71914-80-210mM * 1mLin Water825元

S-腺苷甲硫氨酸對甲苯磺酸鹽 上下游產(chǎn)品信息

"S-腺苷甲硫氨酸對甲苯磺酸鹽"相關(guān)產(chǎn)品信息
甲苯磺酸索拉非尼 二甲苯磺酸鈉 DL-蛋氨酸 S-腺苷-L-蛋氨酸 纈氨酸 對甲苯磺酸 L-蛋氨酸 對氯苯乙酰腈 對甲苯磺酸乙酯 N4-乙基-N4-(2-甲氧基乙基)-2-甲基-對苯二胺-雙(對-甲基苯磺酸)鹽 三甲基氫氧化硫 L-乙硫胺酸 DL-丁基巰基丁氨酸 S-腺苷甲硫氨酸對甲苯磺酸鹽
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