S-腺苷甲硫氨酸對甲苯磺酸鹽
中文名稱 | S-腺苷甲硫氨酸對甲苯磺酸鹽 |
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中文同義詞 | S-腺甙甲硫氨酸對甲苯磺酸鹽;S-腺苷甲硫氨酸對甲苯磺酸鹽;S-腺苷甲硫氨酸對甲苯磺酸鹽(S-腺甙甲硫氨酸對甲苯磺酸鹽);S-腺苷甲硫氨酸對甲苯磺酸鹽 17176-17-9/;腺苷蛋氨酸甲苯磺酸鹽;S-腺苷-L-蛋氨酸甲磺酸鹽;S-腺苷-L-甲硫氨酸(苯磺酸鹽) |
英文名稱 | S-Adenosyl-L-methionine tosylate |
英文同義詞 | S-ADENOSYLMETHIONINE TOSYLATE;S-Adenosyl-L-methionine tosylate;S-(5'-ADENOSYL)-L-METHIONINE P-TOLUENESULFONATE;S-(5'-ADENOSYL)-L-METHIONINE TOLUENE-4-SULFONATE;SAM-E;S-(5'-ADENOSYL)-L-METHIONINETOLUENE- &;S-ADENOSYL-L-METHIONINE (SAME);S-(5''-Adenosyl)-L-methionine-4-toluenesulfonate |
CAS號 | 71914-80-2 |
分子式 | C15H23N6O5S.C7H7O3S |
分子量 | 570.64 |
EINECS號 | |
相關(guān)類別 | 醫(yī)藥原料;化學(xué)試劑;醫(yī)用原料 |
Mol文件 | 71914-80-2.mol |
結(jié)構(gòu)式 |
S-腺苷甲硫氨酸對甲苯磺酸鹽 性質(zhì)
儲存條件 | −20°C |
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溶解度 | H2O:0.1 g/mL,澄清 |
S-Adenosyl-L-methionine (Ademetionine) is involved in three main metabolic pathways: 1) methylation, as the principal source of methyl groups in the body; 2) transsulfuration, S-Adenosyl-L-methionine forms S-Adenosylhomocysteine (SAH) and then converted to homocysteine (Hcy) which can be converted to cystathionine then to cysteine and the sulfate (SO4) donated to other metabolic intermediates; and 3) aminopropylation, as S-Adenosyl-L-methionine plays an important role in the synthesis of polyamines which can eventually form and recycle methionine.
In vitro studies using human articular chondrocytes have shown S-Adenosyl-L-methionine-induced increases in proteoglycan synthesis and proliferation rates in rabbits.
Mice lacking methionine adenosyltransferase 1a (Mat1a) have reduced hepatic S-Adenosyl-L-methionine levels and develop oxidative stress, steatohepatitis, and hepatocellular carcinoma (HCC). However, injury and HCC also occur if hepatic S-Adenosyl-L-methionine level is excessive chronically. Thus a normal hepatic S-Adenosyl-L-methionine level is necessary to maintain liver health and prevent injury and HCC.
安全信息
WGK Germany | 3 |
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F | 1-10 |
提供商 | 語言 |
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英文
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更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
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2024/11/08 | HY-B0617A | S-腺苷甲硫氨酸對甲苯磺酸鹽 S-Adenosyl-L-methionine tosylate | 71914-80-2 | 50mg | 750元 |
2024/11/08 | HY-B0617A | S-腺苷甲硫氨酸對甲苯磺酸鹽 S-Adenosyl-L-methionine tosylate | 71914-80-2 | 10mM * 1mLin Water | 825元 |