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ChemicalBook > Product Catalog >Natural Products >Alkaloids >Oxindole

Oxindole

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CAS:59-48-3
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CAS:59-48-3
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Oxindole manufacturers

  • Oxindole
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  • 2025-04-27
  • CAS:59-48-3
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  • CAS:59-48-3
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Related articles

  • Synthesis of 2-Oxindole
  • 2-Oxindole is a bicyclic nitrogen heterocycle with a carbonyl function at position 2 of the fused pyrrole ring, having two pos....
  • Jan 24,2022
Oxindole Basic information
Product Name:Oxindole
Synonyms:OXINDOL;OXINDOLE;O-(AMINOPHENYL)ACETIC ACID LACTAM;TIMTEC-BB SBB004215;2-Oxo-2,3-dihydroindole;NSC 274863;1,3-dihydro-2h-indol-2-on;1,3-Dihydroindol-2-one
CAS:59-48-3
MF:C8H7NO
MW:133.15
EINECS:200-429-5
Product Categories:Indoles and derivatives;Indoline & Oxindole;blocks;IndolesOxindoles;Heterocycle-Indole series;Indoles;Indole Derivatives;Aromatic Phenylacetic Acids and Derivatives
Mol File:59-48-3.mol
Oxindole Structure
Oxindole Chemical Properties
Melting point 123-128 °C(lit.)
Boiling point 227 °C73 mm Hg(lit.)
density 1.1475 (rough estimate)
refractive index 1.5282 (estimate)
Fp 194-196°C/17mm
storage temp. Sealed in dry,Room Temperature
solubility 9.1g/l
pka14.77±0.20(Predicted)
form Solid
color Light Brown
Water Solubility insoluble
BRN 114692
CAS DataBase Reference59-48-3(CAS DataBase Reference)
NIST Chemistry Reference2H-Indol-2-one, 1,3-dihydro-(59-48-3)
EPA Substance Registry SystemOxindol (59-48-3)
Safety Information
Hazard Codes Xn
Risk Statements 22
Safety Statements 22-24/25
RIDADR 2811
WGK Germany 3
RTECS NM2080500
HazardClass 6.1(b)
PackingGroup III
HS Code 29337900
MSDS Information
ProviderLanguage
Oxindole English
SigmaAldrich English
ACROS English
ALFA English
Oxindole Usage And Synthesis
Chemical Propertiesbeige to yellowish-orange or pinkish-brown powder
UsesIndole analogue; shows pharmacological activity
UsesOxindole is considered as indole analogue, which shows pharmacological activity.
DefinitionChEBI: Indolin-2-one is an indolinone carrying an oxo group at position 2. It is an indolinone and a gamma-lactam.
HazardCauses flaccid paralysis without anesthesia (usually neuromuscular blockage), changes in motor activity, and ataxia in oral and intraperitoneal lethal-dose studies of mice;  May cause irritation; Harmful by ingestion.
Solubility in organicsOxindole is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF), which should be purged with an inert gas. The solubility of oxindole in ethanol and DMF is approximately 10 mg/ml and approximately 3 mg/ml in DMSO. Oxindole is sparingly soluble in aqueous buffers.
Tag:Oxindole(59-48-3) Related Product Information
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