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59-48-3

中文名稱 2-吲哚酮
英文名稱 Oxindole
CAS 59-48-3
EINECS 編號 200-429-5
分子式 C8H7NO
MDL 編號 MFCD00005711
分子量 133.15
MOL 文件 59-48-3.mol
更新日期 2025/05/30 19:49:16
59-48-3 結構式 59-48-3 結構式

基本信息

中文別名
1,3-二氫-吲哚-2-酮
2-吲哚酮
吲哚二酮
2-吲哚酮(2-羥基吲哚)
羥吲哚
氧化吲哚
2-羥吲哚
鄰胺苯乙酸內(nèi)醯胺
羥吲哚, 97+%
英文別名
1,3-DIHYDRO-2H-INDOL-2-ONE
1,3-DIHYDRO-INDOLE-2-ONE
2-(AMINOPHENYL)ACETIC ACID LACTAM
2-HYDROXYINDOLE
2-INDOLINONE
2-KETOINDOLINE
2-OXINDOLE
AKOS B028811
INDOLIN-2-ONE
INDOLINONE, 2-
O-(AMINOPHENYL)ACETIC ACID LACTAM
OXINDOL
OXINDOLE
TIMTEC-BB SBB004215
1,3-dihydro-2h-indol-2-on
1,3-Dihydro-indol-2-one
1,3-Dihydroindol-2-one
2,3-dihydroindol-2-one
2,3-Dihydroindole-2-one
2H-Indol-2-one,1,3-dihydro-
所屬類別
天然產(chǎn)物:生物堿

物理化學性質(zhì)

外觀性狀白色或微黃色結晶粉末,熔點121-124°C。
熔點123-128 °C(lit.)
沸點227 °C73 mm Hg(lit.)
密度1.1475 (rough estimate)
折射率1.5282 (estimate)
閃點194-196°C/17mm
儲存條件Sealed in dry,Room Temperature
溶解度9.1g/l
酸度系數(shù)(pKa)14.77±0.20(Predicted)
形態(tài)Solid
顏色Light Brown
水溶解性insoluble
檢測方法HPLC,NMR
BRN114692
CAS 數(shù)據(jù)庫59-48-3(CAS DataBase Reference)
NIST化學物質(zhì)信息2H-Indol-2-one, 1,3-dihydro-(59-48-3)
EPA化學物質(zhì)信息Oxindol (59-48-3)

安全數(shù)據(jù)

危險性符號(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險性描述H302
危險品標志Xn
危險類別碼R22
安全說明S22-S24/25
危險品運輸編號2811
WGK Germany3
RTECS號NM2080500
危險等級6.1(b)
包裝類別III
海關編碼29337900

應用領域

用途1

吲哚類似物; 顯示藥理活性。

化學品安全說明書(MSDS)

常見問題列表

應用
2-吲哚酮為酮類衍生物,可用作醫(yī)藥中間體。
生物活性
Oxindole (2-indolone, 2-Oxindole, Indolin-2-one)是芳香族雜環(huán)有機化合物,當劑量過量時,可引起鎮(zhèn)靜、肌無力、低血壓和昏迷。
體外研究

Oxindole (Indolin-2-one) is a bicyclic structure consisting of a benzene ring fused to 2-pyrrolidone. Substituted indolinones can be referred as ‘privileged structures’ owing to their excellent binding affinity for many receptors and to the number of approved drugs containing this scaffold. Oxindole has been found in tissues and fluids of mammals as well as natural products produced by a range of plants, bacteria and invertebrates. 2-indolinone derivatives possess diverse range of pharmacological activities including anti-cancer, anti-HIV, anti-diabetic, antibacterial, antioxidant, kinase inhibitory, AChE inhibitory, anti-leishmanial, b3 adrenergic receptor agonistic, phosphatase inhibitory, analgesic, spermicidal, vasopressin antagonists, progesterone antagonists, neuroprotection, NMDA blocker and sleep inducing activities.

2-吲哚酮價格(試劑級)
報價日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價格
2025/05/22A187642-吲哚酮,97+%
Oxindole, 97+%
59-48-35g252元
2025/05/22A187642-吲哚酮,97+%
Oxindole, 97+%
59-48-325g754元
2025/05/22A187642-吲哚酮,97+%
Oxindole, 97+%
59-48-3100g2722元
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