isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate 基本信息
| 中文名稱 | isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate |
|---|---|
| 中文同義詞 | 替諾福韋拉酚氨酯雜質(zhì)08;替諾福韋艾拉酚胺非對映異構(gòu)體(RRR);(S)-2-氨基丙酸異丙酯鹽酸鹽 L-丙氨酸異丙酯鹽酸鹽(R)-丙胺酸異丙酯2-{(R)-[((R)-1-(6-氨基-9H-嘌呤-9-基)-1-甲基乙氧基]甲基}-苯氧基磷?；?替諾福韋艾拉酚胺雜質(zhì)08;替諾福韋雜質(zhì)41;替諾福韋艾拉酚胺酯雜質(zhì)7;替諾福韋拉酚氨酯雜質(zhì)7;TAF-IM-C(9-{(R)-2-[({[(R)-1-(異丙基氧基羰基)乙基]氨基}-苯氧基磷?；?甲氧基]丙基}腺嘌呤) |
| 英文名稱 | isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate |
| 英文同義詞 | isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate;isopropyl (((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate;Tenofovir Alafenamide Impurity 16;isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate fumarate;D-Alanine, N-[(R)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester;isopropyl(((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate |
| CAS號 | 2053424-88-5 |
| 分子式 | C21H29N6O5P |
| 分子量 | 476.47 |
| EINECS號 | |
| 相關(guān)類別 | 替諾福韋拉酚氨酯雜質(zhì);對照品-雜質(zhì)對照品;替諾福韋艾拉酚胺雜質(zhì);045-替諾福韋拉酚氨酯 |
| Mol文件 | 2053424-88-5.mol |
| 結(jié)構(gòu)式 |  |
isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate 性質(zhì)
| 熔點 | 134 - 138°C |
|---|---|
| 沸點 | 640.4±65.0 °C(Predicted) |
| 密度 | 1.39±0.1 g/cm3(Predicted) |
| 儲存條件 | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| 溶解度 | 可溶于氯仿（輕微）、甲醇（輕微、超聲處理） |
| 酸度系數(shù)(pKa) | 4.21±0.10(Predicted) |
| 形態(tài) | 固體 |
| 顏色 | 白色至類白色 |
| 穩(wěn)定性 | 吸濕性 |