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Nucleoside drugs

Many of the purine pyrimidine nucleoside analogues, which are promising antiviral compounds, are antiviral in tissue culture and in vivo. The compounds with selective inhibition of the virus, low toxicity, and effective in animals develop into nuclei Glycosides antiviral drugs. Currently, nucleoside drugs that are effective in clinical applications, have commodities, and have been recognized include iodine glycosides, trifluorothymidine, cyclosine, a sugar adenosine, acyclovir and so on. Nucleoside drugs that have a certain effect in clinical trials, have goods in some countries, yet to be recognized include ribavirin, arabinosyl adenosine monophosphate, bromide uridine and so on. Clinical trials are under way to observe the effect include fluoro-iodine cytosine. The new anti-viral nucleoside compounds have been reported is still in research and development. Nucleoside analogs are nucleic acid antimetabolites that are structurally analogous to nucleic acid precursors, competing for nucleic acid synthase enzyme systems, replacing normal nucleic acid precursors, or inhibiting nucleic acid synthetases, blocking viral or cellular nucleic acid synthesis, selectively inhibiting viral nucleic acids , while have little effect on the synthesis of nucleic acid.
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Structure Chemical Name CAS MF
5-Chlorouridine 5-Chlorouridine 2880-89-9 C9H11ClN2O6
2'-Deoxy-5'-O-DMT-2'-fluorouridine 2'-Deoxy-5'-O-DMT-2'-fluorouridine 146954-74-7 C30H29FN2O7
6-THIOXANTHINE 6-THIOXANTHINE 2002-59-7 C5H4N4OS
6-Methylthioguanine 6-Methylthioguanine 1198-47-6 C6H7N5S
2'-Deoxyadenosine 5'-triphosphate 2'-Deoxyadenosine 5'-triphosphate 1927-31-7 C10H16N5O12P3
2′,3′-O-Isopropylideneuridine 2′,3′-O-Isopropylideneuridine 362-43-6 C12H16N2O6
5'-O-(4,4'-dimethoxytrityl)-2'-deoxyinosine 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyinosine 93778-57-5 C31H30N4O6
2',3',5'-Tri-O-acetyl-2-aMino-6-chloropurine Riboside 2',3',5'-Tri-O-acetyl-2-aMino-6-chloropurine Riboside 16321-99-6 C16H18ClN5O7
2-THIOURIDINE 2-THIOURIDINE 20235-78-3 C9H12N2O5S
2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE 2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE 159414-98-9 C32H32FN3O7
4-THIOURIDINE 4-THIOURIDINE 13957-31-8 C9H12N2O5S
2',3'-Dideoxythymidine 2',3'-Dideoxythymidine 3416-05-5 C10H14N2O4
1-(4-NITROBENZENESULFONYL)-1H-1,2,4-TRIAZOLE 1-(4-NITROBENZENESULFONYL)-1H-1,2,4-TRIAZOLE 57777-84-1 C8H6N4O4S
5-N-PROPYLURACIL 5-N-PROPYLURACIL 19030-75-2 C7H10N2O2
4,5,6-TRIAMINOPYRIMIDINE SULFATE 4,5,6-TRIAMINOPYRIMIDINE SULFATE 49721-45-1 C4H9N5O4S
5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-METHYLURIDINE 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-METHYLURIDINE 103285-22-9 C31H32N2O8
5-Iodocytidine 5-Iodocytidine 1147-23-5 C9H12IN3O5
N4-ACETYL-2'-DEOXYCYTIDINE N4-ACETYL-2'-DEOXYCYTIDINE 32909-05-0 C11H15N3O5
Deoxycytidine triphosphate trisodium salt Deoxycytidine triphosphate trisodium salt 109909-44-6 C9H17N3NaO13P3
5-IODO-1,3-DIMETHYLURACIL 5-IODO-1,3-DIMETHYLURACIL 40738-83-8 C6H7IN2O2
6-CHLOROPURINE-2'-DEOXYRIBOSIDE 6-CHLOROPURINE-2'-DEOXYRIBOSIDE 4594-45-0 C10H11ClN4O3
CYTIDINE 3'-MONOPHOSPHATE CYTIDINE 3'-MONOPHOSPHATE 84-52-6 C9H14N3O8P
4,5,6-TRIAMINOPYRIMIDINE SULFATE 4,5,6-TRIAMINOPYRIMIDINE SULFATE 6640-23-9 C4H11N5O5S
5'-Tosyladenosine 5'-Tosyladenosine 5135-30-8 C17H19N5O6S
DIHYDROTHYMINE DIHYDROTHYMINE 696-04-8 C5H8N2O2
1,3-Dimethyluric acid 1,3-Dimethyluric acid 944-73-0 C7H8N4O3
KINETIN RIBOSIDE KINETIN RIBOSIDE 4338-47-0 C15H17N5O5
NECA NECA 35920-39-9 C12H16N6O4
8-BROMOADENINE 8-BROMOADENINE 6974-78-3 C5H4BrN5
N4-Acetylcytidine N4-Acetylcytidine 3768-18-1 C11H15N3O6
5-IODOTUBERCIDIN 5-IODOTUBERCIDIN 24386-93-4 C11H13IN4O4
6-Methylpurine 6-Methylpurine 2004-03-7 C6H6N4
2-Aminopurine riboside 2-Aminopurine riboside 4546-54-7 C10H13N5O4
6-AZAURIDINE 6-AZAURIDINE 54-25-1 C8H11N3O6
2',3'-Dideoxyguanosine 2',3'-Dideoxyguanosine 85326-06-3 C10H13N5O3
2'-Azido-2'-deoxyuridine 2'-Azido-2'-deoxyuridine 26929-65-7 C9H11N5O5
N6-METHYL-2'-DEOXY-ADENOSINE N6-METHYL-2'-DEOXY-ADENOSINE 2002-35-9 C11H15N5O3
2'-DEOXYADENOSINE-5'-TRIPHOSPHATE DISODIUM SALT 2'-DEOXYADENOSINE-5'-TRIPHOSPHATE DISODIUM SALT 74299-50-6 C10H17N5NaO12P3
2'-O-Methylguanosine 2'-O-Methylguanosine 2140-71-8 C11H15N5O5
7-METHYLXANTHINE 7-METHYLXANTHINE 552-62-5 C6H6N4O2
Fialuridine Fialuridine 69123-98-4 C9H10FIN2O5
2,6-Diaminopurine 2'-deoxyriboside 2,6-Diaminopurine 2'-deoxyriboside 4546-70-7 C10H14N6O3
2'-Deoxy-2'-fluoroguanosine 2'-Deoxy-2'-fluoroguanosine 78842-13-4 C10H12FN5O4
URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT 21931-53-3 C9H12N2Na2O12P2
2,4-MESITYLENEDISULFONYL DICHLORIDE 2,4-MESITYLENEDISULFONYL DICHLORIDE 68985-08-0 C9H10Cl2O4S2
2',3'-Dideoxyuridine 2',3'-Dideoxyuridine 5983-09-5 C9H12N2O4
Diethyl chlorothiophosphate Diethyl chlorothiophosphate 2524-04-1 C4H10ClO2PS
4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) 65996-58-9 C6H6N4O
Bucladesine sodium Bucladesine sodium 16980-89-5 C18H25N5NaO8P
5-Bromo-2'-deoxycytidine 5-Bromo-2'-deoxycytidine 1022-79-3 C9H12BrN3O4
8-BROMOADENOSINE 8-BROMOADENOSINE 2946-39-6 C10H12BrN5O4
2',3',5'-Tri-O-acetyl-D-adenosine 2',3',5'-Tri-O-acetyl-D-adenosine 7387-57-7 C16H19N5O7
1,3-BENZODITHIOLYLIUM TETRAFLUOROBORATE 1,3-BENZODITHIOLYLIUM TETRAFLUOROBORATE 57842-27-0 C7H5BF4S2
5-IODOCYTOSINE 5-IODOCYTOSINE 1122-44-7 C4H4IN3O
2,3,5-Tri-O-benzoyl-beta-D-ribofuranosyl cyanide 2,3,5-Tri-O-benzoyl-beta-D-ribofuranosyl cyanide 23316-67-8 C27H21NO7
7,9-DIMETHYLGUANINE 7,9-DIMETHYLGUANINE 524-35-6 C7H9N5O
6-AMINO-2-HYDROXYPURINE 6-AMINO-2-HYDROXYPURINE 49722-90-9 C10H12N10O6S
5'-O-TRITYLURIDINE 5'-O-TRITYLURIDINE 6554-10-5 C28H26N2O6
UMP UMP 58-97-9 C9H13N2O9P
UDP SODIUM SALT UDP SODIUM SALT 19817-91-5 C9H15N2NaO12P2
N6,N6-DIMETHYLADENOSINE N6,N6-DIMETHYLADENOSINE 2620-62-4 C12H17N5O4
2-THIOCYTIDINE 2-THIOCYTIDINE 13239-97-9 C9H13N3O4S
7-DEAZA-7-IODO-2'-DEOXYGUANOSINE 7-DEAZA-7-IODO-2'-DEOXYGUANOSINE 172163-62-1 C11H13IN4O4
5'-INOSINIC ACID DISODIUM SALT HYDRATE 5'-INOSINIC ACID DISODIUM SALT HYDRATE 20813-76-7 C10H16N4NaO9P
5μ-Inosinic acid hydrate disodium salt, I-5μ-P, IMP, Inosinic Acid 5μ-Inosinic acid hydrate disodium salt, I-5μ-P, IMP, Inosinic Acid 352195-40-5 C10H16N4NaO9P
N4-Acetyl-2'-Fluoro-2'-deoxycytidine N4-Acetyl-2'-Fluoro-2'-deoxycytidine 159414-97-8 C11H14FN3O5
5-PROPYL-2-THIOURACIL 5-PROPYL-2-THIOURACIL 2954-52-1 C7H10N2OS
7-DEAZA-2'-DEOXYADENOSINE 7-DEAZA-2'-DEOXYADENOSINE 60129-59-1 C11H14N4O3
2'-Deoxyuridine-5'-triphosphate trisodium salt 2'-Deoxyuridine-5'-triphosphate trisodium salt 102814-08-4 C9H16N2NaO14P3
7-DEAZA-2'-DEOXYGUANOSINE 7-DEAZA-2'-DEOXYGUANOSINE 86392-75-8 C11H14N4O4
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine 23669-79-6 C30H30N2O7
Potassium orotate Potassium orotate 24598-73-0 C5H3KN2O4
5-HYDROXYMETHYL-2'-DEOXYURIDINE 5-HYDROXYMETHYL-2'-DEOXYURIDINE 5116-24-5 C10H14N2O6
2,4,5,6-TETRAMETHYLBENZENEDISULFONYL DICHLORIDE 2,4,5,6-TETRAMETHYLBENZENEDISULFONYL DICHLORIDE 97997-76-7 C10H12Cl2O4S2
9-Methyladenine 9-Methyladenine 700-00-5 C6H7N5
CCPA CCPA 37739-05-2 C15H20ClN5O4
2'-Amino-2'-deoxyguanosine 2'-Amino-2'-deoxyguanosine 60966-26-9 C10H14N6O4
2-Amino-9-[(2R,4S,5S)-4-amino-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one 2-Amino-9-[(2R,4S,5S)-4-amino-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one 66323-49-7 C10H14N6O3
3'-O-methylguanosine 3'-O-methylguanosine 10300-27-3 C11H15N5O5
8-BROMO-2'-DEOXYGUANOSINE 8-BROMO-2'-DEOXYGUANOSINE 13389-03-2 C10H12BrN5O4
5'-IODO-5'-DEOXYADENOSINE 5'-IODO-5'-DEOXYADENOSINE 4099-81-4 C10H12IN5O3
N6-ISOPENTENYLADENOSINE-D6 N6-ISOPENTENYLADENOSINE-D6 7724-76-7 C15H21N5O4
2'-Fluoro-2'-deoxyadenosine 2'-Fluoro-2'-deoxyadenosine 64183-27-3 C10H12FN5O3
3'-O-Methyl-D-adenosine 3'-O-Methyl-D-adenosine 10300-22-8 C11H15N5O4
N4-BENZOYL-5'-O-DMT-CYTIDINE N4-BENZOYL-5'-O-DMT-CYTIDINE 81246-76-6 C37H35N3O8
DMT-dC(bz) Phosphoramidite DMT-dC(bz) Phosphoramidite 102212-98-6 C46H52N5O8P
N4-BENZOYL-2'-O-METHYLCYTIDINE N4-BENZOYL-2'-O-METHYLCYTIDINE 52571-45-6 C17H19N3O6
6-AZA-2-THIOTHYMINE 6-AZA-2-THIOTHYMINE 615-76-9 C4H5N3OS
3-METHYLADENINE 3-METHYLADENINE 5142-23-4 C6H7N5
Cytidine-5'-diphosphate disodium salt Cytidine-5'-diphosphate disodium salt 54394-90-0 C9H16N3NaO11P2
5-Fluorouridine 5-Fluorouridine 77180-80-4 C9H11FN2O6
2',3',5'-Tri-O-acetylinosine 2',3',5'-Tri-O-acetylinosine 3181-38-2 C16H18N4O8
1-METHYLADENINE 1-METHYLADENINE 5142-22-3 C6H7N5
5'-DEOXY-5'-METHYLTHIOADENOSINE 5'-DEOXY-5'-METHYLTHIOADENOSINE 2457-80-9 C11H15N5O3S
N6-Benzoyl-2'-deoxyadenosine N6-Benzoyl-2'-deoxyadenosine 305808-19-9 C17H19N5O5
RIBOFLAVIN-5'-PHOSPHATE SODIUM SALT DIHYDRATE RIBOFLAVIN-5'-PHOSPHATE SODIUM SALT DIHYDRATE 6184-17-4 C17H24N4NaO10P
5-ETHYL-2-THIOURACIL 5-ETHYL-2-THIOURACIL 34171-37-4 C6H8N2OS
3'-Amino-2',3'-dideoxyadenosine 3'-Amino-2',3'-dideoxyadenosine 7403-25-0 C10H14N6O2
2'-Amino-D-uridine 2'-Amino-D-uridine 26889-39-4 C9H13N3O5
6-Methoxypurine 6-Methoxypurine 1074-89-1 C6H6N4O
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