SU 6668
- $5 - $1350
- Product name: SU 6668
- CAS: 210644-62-5
- MF: C18H18N2O3
- MW: 310.35
- EINECS:
- MDL Number:MFCD09743433
- Synonyms:SU 6668;3-(2,4-Dimethyl-5-(2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl)-propionic acid;1H-Pyrrole-3-propanoic acid, 5-((Z)-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-;5-((Z)-1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-propanoic acid;PDGFR Tyrosine Kinase Inhibitor VI, SU6668;3-[2,4-dimethyl-5-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoicacid;PDGFR Tyrosine Kinase Inhibitor VI, SU6668 - CAS 210644-62-5 - Calbiochem;3-(2,4-Dimethyl-5-{[(3Z)-2-oxo-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid
16 prices
Selected condition:
Brand
- Ambeed
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mg
- 25mg
- 5mg
- 10
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- ManufacturerAmbeed
- Product numberA146183
- Product descriptionSU6668 97%
- Packaging25mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA146183
- Product descriptionSU6668 97%
- Packaging5g
- Price$405
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM147636
- Product description(Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoicacid 95%+
- Packaging1g
- Price$491
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0102969
- Product description(Z)-Orantinib 99.02%
- Packaging100mg
- Price$756
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0102969
- Product description(Z)-Orantinib 99.02%
- Packaging50mg
- Price$432
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0102969
- Product description(Z)-Orantinib 99.02%
- Packaging10mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11166850
- Product descriptionSU6668 97%
- Packaging1g
- Price$547
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11166850
- Product descriptionSU6668 97%
- Packaging250mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN20031
- Product descriptionSU6668
- Packaging25mg
- Price$56
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN20031
- Product descriptionSU6668
- Packaging250mg
- Price$209
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number132613
- Product description(Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoicacid 97%
- Packaging250mg
- Price$537
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number132613
- Product description(Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoicacid 97%
- Packaging1g
- Price$1350
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberCDS023028
- Product description2,4-Dimethyl-5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-pyrrole-3-propanoic acid
- Packaging100MG
- Price$308
- Updated2023-01-07
- Buy
- ManufacturerTocris
- Product number3335
- Product descriptionSU6668 ≥99%(HPLC)
- Packaging10
- Price$208
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberD457088
- Product description(Z)?-?3-?(2,?4-?Dimethyl-?5-?((2-?oxoindolin-?3-?ylidene)?methyl)?-?1H-?pyrrol-?3-?yl)?propanoicacid(SU-6668)
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number256776
- Product descriptionSU 6668
- Packaging10mg
- Price$466
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Ambeed | A146183 | SU6668 97% | 25mg | $5 | 2021-12-16 | Buy |
Ambeed | A146183 | SU6668 97% | 5g | $405 | 2021-12-16 | Buy |
Chemenu | CM147636 | (Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoicacid 95%+ | 1g | $491 | 2021-12-16 | Buy |
ChemScene | CS-0102969 | (Z)-Orantinib 99.02% | 100mg | $756 | 2021-12-16 | Buy |
ChemScene | CS-0102969 | (Z)-Orantinib 99.02% | 50mg | $432 | 2021-12-16 | Buy |
ChemScene | CS-0102969 | (Z)-Orantinib 99.02% | 10mg | $108 | 2021-12-16 | Buy |
Crysdot | CD11166850 | SU6668 97% | 1g | $547 | 2021-12-16 | Buy |
Crysdot | CD11166850 | SU6668 97% | 250mg | $218 | 2021-12-16 | Buy |
CSNpharm | CSN20031 | SU6668 | 25mg | $56 | 2021-12-16 | Buy |
CSNpharm | CSN20031 | SU6668 | 250mg | $209 | 2021-12-16 | Buy |
Matrix Scientific | 132613 | (Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoicacid 97% | 250mg | $537 | 2021-12-16 | Buy |
Matrix Scientific | 132613 | (Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoicacid 97% | 1g | $1350 | 2021-12-16 | Buy |
Sigma-Aldrich | CDS023028 | 2,4-Dimethyl-5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-pyrrole-3-propanoic acid | 100MG | $308 | 2023-01-07 | Buy |
Tocris | 3335 | SU6668 ≥99%(HPLC) | 10 | $208 | 2021-12-16 | Buy |
TRC | D457088 | (Z)?-?3-?(2,?4-?Dimethyl-?5-?((2-?oxoindolin-?3-?ylidene)?methyl)?-?1H-?pyrrol-?3-?yl)?propanoicacid(SU-6668) | 5mg | $90 | 2021-12-16 | Buy |
Usbiological | 256776 | SU 6668 | 10mg | $466 | 2021-12-16 | Buy |
Properties
storage temp. :+2C to +8C
solubility :DMSO : 50 mg/mL (161.11 mM; Need ultrasonic)
form :Dark yellow solid
color :Orange to red
solubility :DMSO : 50 mg/mL (161.11 mM; Need ultrasonic)
form :Dark yellow solid
color :Orange to red
Safety Information
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Description
PDGFR Tyrosine Kinase Inhibitor VI, SU6668 is a cell-permeable indolinone compound that acts as a potent ATP-competitive inhibitor against RTKs (receptor tyrosine kinases) Kit, PDGFRβ, VEGFR2 (Flk-1/KDR), FGFR1 activity in vitro (IC50 = 0.01, 0.1, 3.9, and 3.8 M, respectively) and PDGF/VEGF/bFGF-mediated angiogenesis and tumor development. Although initially characterized as an RTK inhibitor, SU6668 is now also known to target ser/thr kinases Aurora A, Aurora B, TBK1 (NAK/T2K), and AMPK (IC50 = 0.85, 0.047, 1.4, and 1.8 M, respectively), as well as non-receptor TKs Lyn and Yes (IC50 = 4.3 and 5.8 M, respectively).More related product prices
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