SB 225002
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- $50 - $2180
- Product name: SB 225002
- CAS: 182498-32-4
- MF: C13H10BrN3O4
- MW: 352.14
- EINECS:
- MDL Number:MFCD00954637
- Synonyms:SB 225002;N-(2-HYDROXY-4-NITROPHENYL)-N'-(2-BROMOPHENYL)UREA;N-(2-BROMOPHENYL)-N'-(2-HYDROXY-4-NITROPHENYL)UREA;1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea;SB 225002 - CAS 182498-32-4 - Calbiochem;SB-225002;SB 225002;Urea, N-(2-bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)-;SB 225002 USP/EP/BP
39 prices
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Brand
- AK Scientific
- Alfa Aesar
- Ambeed
- Apolloscientific
- Arctom
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10mg
- 1mg
- 50
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1g
- 10
- 10g
- ManufacturerAK Scientific
- Product number2703AH
- Product description1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea
- Packaging10g
- Price$1747
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2703AH
- Product description1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea
- Packaging1g
- Price$370
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ65387
- Product descriptionSB 225002
- Packaging5mg
- Price$142
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ65387
- Product descriptionSB 225002
- Packaging10mg
- Price$274
- Updated2023-06-20
- Buy
- ManufacturerAmbeed
- Product numberA149514
- Product descriptionSB 225002 98+%
- Packaging5mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA149514
- Product descriptionSB 225002 98+%
- Packaging10mg
- Price$67
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA149514
- Product descriptionSB 225002 98+%
- Packaging25mg
- Price$88
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA149514
- Product descriptionSB 225002 98+%
- Packaging50mg
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA149514
- Product descriptionSB 225002 98+%
- Packaging1g
- Price$2180
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIFK0040
- Product descriptionSB 225002 >99%
- Packaging5mg
- Price$66
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIFK0040
- Product descriptionSB 225002 >99%
- Packaging10mg
- Price$109
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIFK0040
- Product descriptionSB 225002 >99%
- Packaging25mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS047176
- Product descriptionSB 225002 ≥98%
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13336
- Product descriptionSB 225002 ≥95%
- Packaging5mg
- Price$82
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13336
- Product descriptionSB 225002 ≥95%
- Packaging10mg
- Price$153
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13336
- Product descriptionSB 225002 ≥95%
- Packaging25mg
- Price$362
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2703AH | 1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea | 10g | $1747 | 2021-12-16 | Buy |
| AK Scientific | 2703AH | 1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea | 1g | $370 | 2021-12-16 | Buy |
| Alfa Aesar | J65387 | SB 225002 | 5mg | $142 | 2021-12-16 | Buy |
| Alfa Aesar | J65387 | SB 225002 | 10mg | $274 | 2023-06-20 | Buy |
| Ambeed | A149514 | SB 225002 98+% | 5mg | $51 | 2021-12-16 | Buy |
| Ambeed | A149514 | SB 225002 98+% | 10mg | $67 | 2021-12-16 | Buy |
| Ambeed | A149514 | SB 225002 98+% | 25mg | $88 | 2021-12-16 | Buy |
| Ambeed | A149514 | SB 225002 98+% | 50mg | $115 | 2021-12-16 | Buy |
| Ambeed | A149514 | SB 225002 98+% | 1g | $2180 | 2021-12-16 | Buy |
| Apolloscientific | BIFK0040 | SB 225002 >99% | 5mg | $66 | 2021-12-16 | Buy |
| Apolloscientific | BIFK0040 | SB 225002 >99% | 10mg | $109 | 2021-12-16 | Buy |
| Apolloscientific | BIFK0040 | SB 225002 >99% | 25mg | $218 | 2021-12-16 | Buy |
| Arctom | AS047176 | SB 225002 ≥98% | 5mg | $50 | 2021-12-16 | Buy |
| Cayman Chemical | 13336 | SB 225002 ≥95% | 5mg | $82 | 2024-03-01 | Buy |
| Cayman Chemical | 13336 | SB 225002 ≥95% | 10mg | $153 | 2024-03-01 | Buy |
| Cayman Chemical | 13336 | SB 225002 ≥95% | 25mg | $362 | 2024-03-01 | Buy |
Properties
Boiling point :401.6±45.0 °C(Predicted)
Density :1.793±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :Soluble to 100mM in DMSO and to 50mM in ethanol
form :Yellow solid
pka :5.29±0.10(Predicted)
color :white to beige
Sensitive :Moisture Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :MQBZVUNNWUIPMK-UHFFFAOYSA-N
CAS DataBase Reference :182498-32-4
Density :1.793±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :Soluble to 100mM in DMSO and to 50mM in ethanol
form :Yellow solid
pka :5.29±0.10(Predicted)
color :white to beige
Sensitive :Moisture Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :MQBZVUNNWUIPMK-UHFFFAOYSA-N
CAS DataBase Reference :182498-32-4
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
CXCR2 (IL-8RB) is a seven-transmembrane G protein-coupled receptor whose physiological ligands include IL-8 (CXCL8) and growth related oncogene α (Gro-α; CXCL1). IL-8 and Gro-α are pro-inflammatory CXC chemokines that act as chemoattractants, especially for neutrophils, and promote angiogenesis. SB 225002 is a selective non-peptide inhibitor of CXCR2, inhibiting IL-8 binding to CXCR2 with an IC50 value of 22 nM. SB225002 inhibits neutrophil chemotaxis in response to IL-8 in vitro (IC50 = 20 nM) and blocks neutrophil margination induced by IL-8 in vivo (IC50 = 30 nM). Similarly, SB 225002 reduces neutrophil influx, the production of inflammatory mediators, and tissue damage in TNBS-induced colitis in mice.Related product price
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