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ChemicalBook >> CAS DataBase List >> BML-275

BML-275

BML-275 price.
  • $32 - $1000
  • Product name: BML-275
  • CAS: 1219168-18-9
  • MF: C24H27Cl2N5O
  • MW: 472.41008
  • EINECS:
  • MDL Number:MFCD11112197
  • Synonyms:Dorsomorphin 2HCl (BML-275 2HCl);dorsoMorphin (Hydrochloride);DorsoMorphin, Dihydrochloride Salt, >99%;BML-275,Compound C;6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine hydrochloride (1:2) Dorsomorphin 2HCl;Dorsomorphin-2HCl BML-275;6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine hydrochloride (1:2);BML-275 dihydrochloride
23 prices
Selected condition：
Brand
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAmbeed
  • Product numberA213616
  • Product descriptionDorsomorphindihydrochloride 99+%
  • Packaging50mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA213616
  • Product descriptionDorsomorphindihydrochloride 99+%
  • Packaging100mg
  • Price$199
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA213616
  • Product descriptionDorsomorphindihydrochloride 99+%
  • Packaging250mg
  • Price$298
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA213616
  • Product descriptionDorsomorphindihydrochloride 99+%
  • Packaging1g
  • Price$745
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1372
  • Product descriptionDorsomorphin2HCl
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60096
  • Product descriptionDorsomorphindihydrochloride ≥98%
  • Packaging10mg
  • Price$178
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBD162562
  • Product descriptionDorsomorphin dihydrochloride
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBD162562
  • Product descriptionDorsomorphin dihydrochloride
  • Packaging50mg
  • Price$409
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21207
  • Product descriptionDorsomorphin (hydrochloride) ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21207
  • Product descriptionDorsomorphin (hydrochloride) ≥98%
  • Packaging5mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21207
  • Product descriptionDorsomorphin (hydrochloride) ≥98%
  • Packaging10mg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21207
  • Product descriptionDorsomorphin (hydrochloride) ≥98%
  • Packaging25mg
  • Price$343
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM248296
  • Product descriptionDorsomorphinDihydrochloride 98%
  • Packaging100mg
  • Price$353
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2482
  • Product descriptionDorsomorphin(dihydrochloride) 99.91%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2482
  • Product descriptionDorsomorphin(dihydrochloride) 99.91%
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2482
  • Product descriptionDorsomorphin(dihydrochloride) 99.91%
  • Packaging50mg
  • Price$300
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A213616 Dorsomorphindihydrochloride 99+% 50mg $135 2021-12-16 Buy
Ambeed A213616 Dorsomorphindihydrochloride 99+% 100mg $199 2021-12-16 Buy
Ambeed A213616 Dorsomorphindihydrochloride 99+% 250mg $298 2021-12-16 Buy
Ambeed A213616 Dorsomorphindihydrochloride 99+% 1g $745 2021-12-16 Buy
ApexBio Technology B1372 Dorsomorphin2HCl 5mg $50 2021-12-16 Buy
Arctom CFN60096 Dorsomorphindihydrochloride ≥98% 10mg $178 2021-12-16 Buy
Biosynth Carbosynth BD162562 Dorsomorphin dihydrochloride 10mg $95 2021-12-16 Buy
Biosynth Carbosynth BD162562 Dorsomorphin dihydrochloride 50mg $409 2021-12-16 Buy
Cayman Chemical 21207 Dorsomorphin (hydrochloride) ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 21207 Dorsomorphin (hydrochloride) ≥98% 5mg $116 2024-03-01 Buy
Cayman Chemical 21207 Dorsomorphin (hydrochloride) ≥98% 10mg $153 2024-03-01 Buy
Cayman Chemical 21207 Dorsomorphin (hydrochloride) ≥98% 25mg $343 2024-03-01 Buy
Chemenu CM248296 DorsomorphinDihydrochloride 98% 100mg $353 2021-12-16 Buy
ChemScene CS-2482 Dorsomorphin(dihydrochloride) 99.91% 5mg $60 2021-12-16 Buy
ChemScene CS-2482 Dorsomorphin(dihydrochloride) 99.91% 10mg $90 2021-12-16 Buy
ChemScene CS-2482 Dorsomorphin(dihydrochloride) 99.91% 50mg $300 2021-12-16 Buy

Properties

storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :insoluble in EtOH; insoluble in H2O; ≥11.34 mg/mL in 0.9% NS ; ≥39.93 mg/mL in DMSO:H2O=2:1 ; ≥5.91 mg/mL in DMSO
form :Light yellow powder solid.
color :Yellow
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Dorsomorphin (hydrochloride) is a potent, reversible inhibitor of AMP kinase (AMPK; Ki = 109 nM) that does not exhibit significant activity on structurally related kinases, including ZAPK, SYK, PKCθ, PKA, and JAK3. Dorsomorphin can also dose-dependently inhibit the bone morphogenetic protein type 1 receptors ACTR-I (ALK2), BMPR-IA (ALK3), and BMPR-IB (ALK6). Independent of AMPK inhibition, dorsomorphin, at 10 μM, has additionally been shown to downregulate the Akt/mTOR pathway to induce autophagy in U251 human glioma cells.

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