Picamilon
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- $32 - $745
- Product name: Picamilon
- CAS: 34562-97-5
- MF: C10H12N2O3
- MW: 208.21
- EINECS:1308068-626-2
- MDL Number:MFCD08272808
- Synonyms:4-((Pyridine-3-carbonyl)-amino)-butyric acid;Pikamiline;PikamiloneHCl;3-[(3-Carboxypropyl)carbamoyl]pyridine;PIKAMILON;4-Nicotinoylamino-butylric acid;PIKAMILONE HYDROCHLORIDE;NICOTINOYL-GABA
18 prices
Selected condition：
Brand
- AHH
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- Chemenu
- Chem-Impex
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- SynChem
- TCI Chemical
- TRC
Package
- 5MG
- 100mg
- 250mg
- 500mg
- 1g
- 5g
- 10g
- 25g
- 50g
- ManufacturerAHH
- Product numberMT-19652
- Product description4-(Nicotinamido)butanoicacid 98%
- Packaging5g
- Price$318
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ91513
- Product descriptionPikamilone
- Packaging5g
- Price$92
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0019194
- Product descriptionPIKAMILONE HYDROCHLORIDE 95.00%
- Packaging5MG
- Price$497.76
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29397
- Product descriptionPicamilon
- Packaging100mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29397
- Product descriptionPicamilon
- Packaging250mg
- Price$73
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29397
- Product descriptionPicamilon
- Packaging500mg
- Price$139
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29397
- Product descriptionPicamilon
- Packaging1g
- Price$243
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM178769
- Product descriptionN-(3-Carboxypropyl)nicotinamide 98%
- Packaging10g
- Price$106
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM178769
- Product descriptionN-(3-Carboxypropyl)nicotinamide 98%
- Packaging25g
- Price$214
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number38116
- Product descriptionPicamilon,≥98%(HPLC) ≥98%(HPLC)
- Packaging5G
- Price$145.6
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11139276
- Product description4-(Nicotinamido)butanoicacid 98%
- Packaging25g
- Price$227
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8966
- Product descriptionPikamilone >98%
- Packaging1g
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number011604
- Product descriptionN-(3-Carboxypropyl)nicotinamide
- Packaging1g
- Price$485
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number97705
- Product descriptionNicotinoyl-?3-aminobutyricAcid
- Packaging500mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerSynChem
- Product numberSC-41979
- Product description4-(NICOTINAMIDO)BUTANOIC ACID 95%
- Packaging1g
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerTCI Chemical
- Product numberN0998
- Product descriptionPicamilon >98.0%(HPLC)(T)
- Packaging5g
- Price$137
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-19652 | 4-(Nicotinamido)butanoicacid 98% | 5g | $318 | 2021-12-16 | Buy |
| AK Scientific | J91513 | Pikamilone | 5g | $92 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0019194 | PIKAMILONE HYDROCHLORIDE 95.00% | 5MG | $497.76 | 2021-12-16 | Buy |
| Cayman Chemical | 29397 | Picamilon | 100mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 29397 | Picamilon | 250mg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 29397 | Picamilon | 500mg | $139 | 2024-03-01 | Buy |
| Cayman Chemical | 29397 | Picamilon | 1g | $243 | 2024-03-01 | Buy |
| Chemenu | CM178769 | N-(3-Carboxypropyl)nicotinamide 98% | 10g | $106 | 2021-12-16 | Buy |
| Chemenu | CM178769 | N-(3-Carboxypropyl)nicotinamide 98% | 25g | $214 | 2021-12-16 | Buy |
| Chem-Impex | 38116 | Picamilon,≥98%(HPLC) ≥98%(HPLC) | 5G | $145.6 | 2021-12-16 | Buy |
| Crysdot | CD11139276 | 4-(Nicotinamido)butanoicacid 98% | 25g | $227 | 2021-12-16 | Buy |
| DC Chemicals | DC8966 | Pikamilone >98% | 1g | $300 | 2021-12-16 | Buy |
| Matrix Scientific | 011604 | N-(3-Carboxypropyl)nicotinamide | 1g | $485 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 97705 | Nicotinoyl-?3-aminobutyricAcid | 500mg | $350 | 2021-12-16 | Buy |
| SynChem | SC-41979 | 4-(NICOTINAMIDO)BUTANOIC ACID 95% | 1g | $135 | 2021-12-16 | Buy |
| TCI Chemical | N0998 | Picamilon >98.0%(HPLC)(T) | 5g | $137 | 2024-03-01 | Buy |
Properties
Melting point :211.0 to 215.0 °C
Boiling point :522.4±30.0 °C(Predicted)
Density :1.245
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO (Slightly, Heated), Methanol (Slightly)
form :Solid
pka :4.60±0.10(Predicted)
color :White to Off-White
InChI :InChI=1S/C10H12N2O3/c13-9(14)4-2-6-12-10(15)8-3-1-5-11-7-8/h1,3,5,7H,2,4,6H2,(H,12,15)(H,13,14)
InChIKey :NAJVRARAUNYNDX-UHFFFAOYSA-N
SMILES :C(O)(=O)CCCNC(C1=CC=CN=C1)=O
CAS DataBase Reference :34562-97-5(CAS DataBase Reference)
Boiling point :522.4±30.0 °C(Predicted)
Density :1.245
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO (Slightly, Heated), Methanol (Slightly)
form :Solid
pka :4.60±0.10(Predicted)
color :White to Off-White
InChI :InChI=1S/C10H12N2O3/c13-9(14)4-2-6-12-10(15)8-3-1-5-11-7-8/h1,3,5,7H,2,4,6H2,(H,12,15)(H,13,14)
InChIKey :NAJVRARAUNYNDX-UHFFFAOYSA-N
SMILES :C(O)(=O)CCCNC(C1=CC=CN=C1)=O
CAS DataBase Reference :34562-97-5(CAS DataBase Reference)
Safety Information
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Description
Picamilon: an analogue of the neurotransmitter γ-aminobutyric acid (GABA)Picamilon is a derivative of γ-aminobutyric acid (GABA) and nicotinic acid developed in 1970 by the All-Union Vitamin Research Institute to increase central nervous system (CNS) levels of γ-aminobutyric acid (GABA). Drugs that can mimic or increase GABA activity in the brain have the potential to provide anti-anxiety and anti-convulsive effects. GABA itself, when consumed orally, does not cross the blood-brain barrier. Much research has, therefore, been devoted to developing orally active agents that have GABA-like effects. Both gabapentin (a GABA analogue) and picamilon were designed to be orally administered drugs that cross the blood-brain barrier and provide inhibitory CNS effects. Picamilon, prescribed in dosages from 50 mg to 200 mg, can cross the blood-brain barrier in animal models and, once in the CNS, is hydrolyzed into GABA and nicotinic acid. The released GABA could potentially have inhibitory properties, including anti-anxiety and anti-convulsant effects. Nicotinic acid would also be released, potentially leading to dilation of CNS blood vessels. The FDA has never approved picamilon for use in the USA, but picamilon is used in Russia to treat various neurological conditions[1].
Related product price
- 3-Aminopyridine
$14-875 - L(+)-2-Aminobutyric acid
$6-3418.8 - PYRAZOPHOS
$122
Suppliers and manufacturers
Hubei xin bonus chemical co. LTD
Chongqing Chemdad Co., Ltd
CONIER CHEM AND PHARMA LIMITED
Zhengzhou Alfa Chemical Co.,Ltd
SIMAGCHEM CORP
Hefei TNJ Chemical Industry Co.,Ltd.
