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ChemicalBook >> CAS DataBase List >> NU 6027

NU 6027

NU 6027 price.
  • $32 - $1600
  • Product name: NU 6027
  • CAS: 220036-08-8
  • MF: C11H17N5O2
  • MW: 251.29
  • EINECS:
  • MDL Number:MFCD05664735
  • Synonyms:2,4-Pyrimidinediamine, 6-(cyclohexylmethoxy)-5-nitroso-;ATR/CDK Inhibitor, NU6027 ;2,6-DiaMino-4-(cyclohexylMethoxy)-5-nitrosopyriMidine;ATR/CDK Inhibitor, NU6027 - CAS 220036-08-8 - Calbiochem;NU6027;NU-6027;NU 6027;6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine;NU 6027 USP/EP/BP;inhibit,Ataxia telangiectasia mutated,Cyclin dependent kinase,ATM/ATR,NU 6027,cytotoxicity,NU6027,Inhibitor,NU-6027,CDK2,cisplatin,hydroxyurea,ATR,CDK1,CDK,ATM and RAD3 related,cancer
18 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 50mg
  • 250mg
  • 1g
  • 10mM(in 1mL DMSO)
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number2601AH
  • Product description2,6-Diamino-4-cyclohexylmethoxy-5-nitrosopyrimidine
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2601AH
  • Product description2,6-Diamino-4-cyclohexylmethoxy-5-nitrosopyrimidine
  • Packaging5mg
  • Price$193
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2601AH
  • Product description2,6-Diamino-4-cyclohexylmethoxy-5-nitrosopyrimidine
  • Packaging10mg
  • Price$252
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001271
  • Product descriptionNU6027 95.00%
  • Packaging1MG
  • Price$430
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001271
  • Product descriptionNU6027 95.00%
  • Packaging5MG
  • Price$721.01
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1986
  • Product descriptionNu6027
  • Packaging5mg
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1986
  • Product descriptionNu6027
  • Packaging10mM(in 1mL DMSO)
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1986
  • Product descriptionNu6027
  • Packaging10mg
  • Price$109
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1986
  • Product descriptionNu6027
  • Packaging50mg
  • Price$429
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16177
  • Product descriptionNU 6027 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16177
  • Product descriptionNU 6027 ≥98%
  • Packaging5mg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16177
  • Product descriptionNU 6027 ≥98%
  • Packaging10mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16177
  • Product descriptionNU 6027 ≥98%
  • Packaging50mg
  • Price$533
  • Updated2024-03-01
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8214
  • Product descriptionNU6027 >98%
  • Packaging250mg
  • Price$900
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8214
  • Product descriptionNU6027 >98%
  • Packaging1g
  • Price$1600
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number47988
  • Product descriptionNU6027
  • Packaging10mg
  • Price$630
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2601AH 2,6-Diamino-4-cyclohexylmethoxy-5-nitrosopyrimidine 1mg $133 2021-12-16 Buy
AK Scientific 2601AH 2,6-Diamino-4-cyclohexylmethoxy-5-nitrosopyrimidine 5mg $193 2021-12-16 Buy
AK Scientific 2601AH 2,6-Diamino-4-cyclohexylmethoxy-5-nitrosopyrimidine 10mg $252 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001271 NU6027 95.00% 1MG $430 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001271 NU6027 95.00% 5MG $721.01 2021-12-16 Buy
ApexBio Technology A1986 Nu6027 5mg $69 2021-12-16 Buy
ApexBio Technology A1986 Nu6027 10mM(in 1mL DMSO) $70 2021-12-16 Buy
ApexBio Technology A1986 Nu6027 10mg $109 2021-12-16 Buy
ApexBio Technology A1986 Nu6027 50mg $429 2021-12-16 Buy
Cayman Chemical 16177 NU 6027 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 16177 NU 6027 ≥98% 5mg $86 2024-03-01 Buy
Cayman Chemical 16177 NU 6027 ≥98% 10mg $139 2024-03-01 Buy
Cayman Chemical 16177 NU 6027 ≥98% 50mg $533 2024-03-01 Buy
DC Chemicals DC8214 NU6027 >98% 250mg $900 2021-12-16 Buy
DC Chemicals DC8214 NU6027 >98% 1g $1600 2021-12-16 Buy
Medical Isotopes, Inc. 47988 NU6027 10mg $630 2021-12-16 Buy

Properties

Melting point :252.5-253.7 °C(lit.)
Boiling point :549.2±60.0 °C(Predicted)
Density :1.53±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 15 mg/mL
pka :2.52±0.10(Predicted)
form :Reddish-purple powder
color :lavender

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Cyclin-dependent kinases (CDKs) play a key role in regulating cell division by phosphorylating distinct substrates in different phases of the cell cycle. Cell cycle deregulation in many cancers often results from altered CDK activity. Thus, CDKs are potential pharmacological targets for anticancer agents. NU 6027 inhibits both CDK1 and CDK2 with IC50 values of 2.9 and 2.2 μM, respectively. It has been shown to inhibit cellular ataxia telangiectasia mutated and Rad3-realted kinase activity (IC50 = 6.7 μM) and impair G2/M arrest in various human cancer cells, potentiating the cytotoxic effects of DNA-damaging, anticancer agents such as cisplatin.

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