| Identification | Back Directory | [Name]
NU 6027 | [CAS]
220036-08-8 | [Synonyms]
NU 6027 USP/EP/BP
NU6027;NU-6027;NU 6027
ATR/CDK Inhibitor, NU6027
2,6-DiaMino-4-(cyclohexylMethoxy)-5-nitrosopyriMidine
6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine
2,4-Pyrimidinediamine, 6-(cyclohexylmethoxy)-5-nitroso-
ATR/CDK Inhibitor, NU6027 - CAS 220036-08-8 - Calbiochem | [Molecular Formula]
C11H17N5O2 | [MDL Number]
MFCD05664735 | [MOL File]
220036-08-8.mol | [Molecular Weight]
251.288 |
| Chemical Properties | Back Directory | [Melting point ]
252.5-253.7 °C(lit.)
| [Boiling point ]
549.2±60.0 °C(Predicted) | [density ]
1.53±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
DMSO: 15 mg/mL
| [form ]
Reddish-purple powder | [pka]
2.52±0.10(Predicted) | [color ]
lavender
|
| Hazard Information | Back Directory | [Uses]
NU6027 is a potent cyclin-dependent kinase (CDK) and Rad3-related kinase (ATR) inhibitor. NU6027 has been shown to inhibit tumor cell growth. NU6027 inhibits ATR, impairing G2/M arrest and homologous recombination thus increasing sensitivity to DNA-damaging agents and poly(ADP-ribose) polymerase (PARP) inhibitors | [target]
CDK1 | [storage]
4°C, protect from light |
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| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
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