MonoMethyl auristatin E
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- $49 - $3260
- Product name: MonoMethyl auristatin E
- CAS: 474645-27-7
- MF: C39H67N5O7
- MW: 717.98
- EINECS:
- MDL Number:MFCD22124498
- Synonyms:MonoMethyl auristatin E(MMAE, vedotin);HM-297C-22;MonoMethyl auristatin E;Monomethyl auristatin E, >=98%;MMAE(Monomethyl auristatin E);(2S)-N-[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]-3-methyl-2-(methylamino)butanamide;[3H]-Vedotin;(S)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1R,2R)-1-Hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy
24 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Biorbyt Ltd
- BroadPharm
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
Package
- 002
- 500μg
- 1mg
- 5mg
- 10mg
- 001
- 003
- 25mg
- 50mg
- 100mg
- 250mg
- 1000mg
- 10mM(in 1mL DMSO)
- 1g
- 5g
- ManufacturerAK Scientific
- Product numberY1831
- Product descriptionMonomethylauristatinE
- Packaging5mg
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3631
- Product descriptionMonomethylauristatinE
- Packaging1mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3631
- Product descriptionMonomethylauristatinE
- Packaging5mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3631
- Product descriptionMonomethylauristatinE
- Packaging10mg
- Price$320
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3631
- Product descriptionMonomethylauristatinE
- Packaging10mM(in 1mL DMSO)
- Price$425
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3631
- Product descriptionMonomethylauristatinE
- Packaging50mg
- Price$980
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180827
- Product descriptionMonomethyl auristatin E (MMAE, vedotin) >98%
- Packaging100mg
- Price$838.1
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180827
- Product descriptionMonomethyl auristatin E (MMAE, vedotin) >98%
- Packaging250mg
- Price$1504.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180827
- Product descriptionMonomethyl auristatin E (MMAE, vedotin) >98%
- Packaging1000mg
- Price$2986.9
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-22278
- Product descriptionMMAE 95%
- Packaging250mg
- Price$790
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16267
- Product descriptionMonomethyl Auristatin E ≥95%
- Packaging500μg
- Price$81
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16267
- Product descriptionMonomethyl Auristatin E ≥95%
- Packaging1mg
- Price$152
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16267
- Product descriptionMonomethyl Auristatin E ≥95%
- Packaging5mg
- Price$356
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16267
- Product descriptionMonomethyl Auristatin E ≥95%
- Packaging10mg
- Price$553
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0837
- Product descriptionMonomethylauristatinE 99.92%
- Packaging1g
- Price$960
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0837
- Product descriptionMonomethylauristatinE 99.92%
- Packaging5g
- Price$3260
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | Y1831 | MonomethylauristatinE | 5mg | $49 | 2021-12-16 | Buy |
| ApexBio Technology | A3631 | MonomethylauristatinE | 1mg | $85 | 2021-12-16 | Buy |
| ApexBio Technology | A3631 | MonomethylauristatinE | 5mg | $200 | 2021-12-16 | Buy |
| ApexBio Technology | A3631 | MonomethylauristatinE | 10mg | $320 | 2021-12-16 | Buy |
| ApexBio Technology | A3631 | MonomethylauristatinE | 10mM(in 1mL DMSO) | $425 | 2021-12-16 | Buy |
| ApexBio Technology | A3631 | MonomethylauristatinE | 50mg | $980 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180827 | Monomethyl auristatin E (MMAE, vedotin) >98% | 100mg | $838.1 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180827 | Monomethyl auristatin E (MMAE, vedotin) >98% | 250mg | $1504.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180827 | Monomethyl auristatin E (MMAE, vedotin) >98% | 1000mg | $2986.9 | 2021-12-16 | Buy |
| BroadPharm | BP-22278 | MMAE 95% | 250mg | $790 | 2021-12-16 | Buy |
| Cayman Chemical | 16267 | Monomethyl Auristatin E ≥95% | 500μg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 16267 | Monomethyl Auristatin E ≥95% | 1mg | $152 | 2024-03-01 | Buy |
| Cayman Chemical | 16267 | Monomethyl Auristatin E ≥95% | 5mg | $356 | 2024-03-01 | Buy |
| Cayman Chemical | 16267 | Monomethyl Auristatin E ≥95% | 10mg | $553 | 2024-03-01 | Buy |
| ChemScene | CS-0837 | MonomethylauristatinE 99.92% | 1g | $960 | 2021-12-16 | Buy |
| ChemScene | CS-0837 | MonomethylauristatinE 99.92% | 5g | $3260 | 2021-12-16 | Buy |
Properties
Melting point :>90°C (dec.)
Boiling point :873.5±65.0 °C(Predicted)
Density :1.088±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
pka :13.66±0.20(Predicted)
form :Solid
color :White to Off-White
InChIKey :RJACXSRFJLSJEZ-UIJRFTGLSA-N
SMILES :C(NC(=O)[C@H](C(C)C)NC)(=O)[C@H](C(C)C)N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N1CCC[C@H]1[C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C1=CC=CC=C1)=O)=O)C
CAS DataBase Reference :474645-27-7
Boiling point :873.5±65.0 °C(Predicted)
Density :1.088±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
pka :13.66±0.20(Predicted)
form :Solid
color :White to Off-White
InChIKey :RJACXSRFJLSJEZ-UIJRFTGLSA-N
SMILES :C(NC(=O)[C@H](C(C)C)NC)(=O)[C@H](C(C)C)N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N1CCC[C@H]1[C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C1=CC=CC=C1)=O)=O)C
CAS DataBase Reference :474645-27-7
Safety Information
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Description
Dolastatin 10 is a natural antimitotic and antineoplastic agent that binds to tubulin and inhibits tubulin polymerization. Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is commonly conjugated with monoclonal antibodies directed at antigens specific to cancer cells for tumor-directed cytotoxicity. MMAE is typically coupled to the antibody via a protease-cleavable linker, allowing separation of the drug from the antibody following intracellular localization.More related product prices
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